Hybrid scaffold suitable for regenerating animal tissues and process for producing the scaffold
AssigneeDialybrid S.R.L.
InventorsFrancesco Giovanni Greco, Stefania Adele Riboldi, Sebastiao Nicolau Dentinho Van Uden, Valentina Ilaria Maria Catto, Davide Meroni
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Abstract
A hybrid scaffold is disclosed which is made of materials that define peripheral layers designed to interface with the tissues in the implant site and one or more intermediate layers. The materials are combined to give the scaffold mechanical properties suitable for withstanding the stresses of the implant site. The materials are fibroin for the peripheral layers and polyurethane combined with fibroin for each intermediate layer.
Claims15
A method of producing a mixture of fibroin and polyurethane, the method comprising the following steps:
- dissolving fibroin in formic acid obtaining a first solution of fibroin;
- dissolving polyurethane into a combination of formic acid and dichloromethane obtaining a second solution of polyurethane dissolved in formic acid and dichloromethane;
- mixing the first solution with the second solution together thereby obtaining the mixture of fibroin and polyurethane dissolved in a final combination of formic acid and dichloromethane while avoiding precipitation in the mixture.
Dependencies are inferred from the claim text.