Halogenation of complex organic compounds
AssigneeThe Regents of the University of Michigan
InventorsDavid H. Sherman, Amy E. Fraley, Ashootosh Tripathi
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Abstract
The disclosure provides biocatalysts that halogenate complex chemical compounds in specific and predictable ways. Also disclosed are halogenated complex organic compounds. The disclosure further provides methods for the halogenation of complex chemical compounds and methods of inhibiting the contraction of smooth muscle in mammals.
Claims3
A method of modulating a Ca2+ signaling pathway in a cell of a mammal comprising administering an effective amount of a halogenated complex organic compound to the mammal to modulate the Ca2+ signaling pathway, wherein the halogenated complex organic compound is isomalbrancheamide D.
Dependencies are inferred from the claim text.