Screen exchange device, biological tissue size reduction system comprising same, biological tissue size reduction method using same, and method for separating target substance from relevant biological tissue

A system for reducing a size of a biological tissue, the system comprising:

• a screen exchange device, comprising:
• a disk comprising a plurality of screens, each having at least one through-hole to reduce a size of a biological tissue, the screens having different through-hole characteristics;
• a first cover that covers a first side of the disk and comprises a first opening through which a biological tissue passes;
• a second cover that covers a second side of the disk and comprises a second opening through which the biological tissue passes;
• a housing configured to receive the disk, the first cover and the second cover;
• and
• a manipulator configured to select a screen from the plurality of screens and manipulate the first cover or the second cover such that the selected screen communicates with the first opening and the second opening, wherein the manipulator is disposed inside the housing, wherein the manipulator comprises:
• a first handle configured to rotate the first cover relative to the disk;
• and
• a second handle configured to rotate the second cover relative to the disk:
• a first syringe comprising a first container configured to be coupled to the first opening and receive a biological tissue and a first push rod configured to apply pressure to the first container;
• and
• a second syringe comprising a second container configured to be coupled to the second opening and receive a biological tissue and a second push rod configured to apply pressure to the second container,
• wherein the system takes a form between a first form in which, in response to the first push rod applying the pressure to the first container, the biological tissue of the first container moves to the second container by passing through the first opening, the selected screen, and the second opening in sequence and a second form in which, in response to the second push rod applying the pressure to the second container, the biological tissue of the second container moves to the first container by passing through the second opening, the selected screen, and the first opening in sequence.