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US 12,243,732 B2Granted
Mass spectrometric determination of fatty acids
AssigneeQuest Diagnostics Investments Incorporated
InventorScott Goldman
Life of this patent
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Abstract
The invention relates to the detection of fatty acids. In a particular aspect, the invention relates to methods for detecting very long chain fatty acids and branched chain fatty acids by mass spectrometry.
Claims10
A method for determining an amount of one or more underivatized docosanoic acid, tetracosanoic acid, and hexacosanoic acid in a sample by mass spectrometry, the method comprising:
- (a) subjecting the sample containing an amount of one or more docosanoic acid, tetracosanoic acid, and/or hexacosanoic acid to an ionization source to generate one or more underivatized docosanoic acid, tetracosanoic acid, and/or hexacosanoic acid ions detectable by mass spectrometry;
- (b) determining an amount of the one or more underivatized docosanoic acid, tetracosanoic acid, and/or hexacosanoic acid ions by mass spectrometry;
- and
- (c) determining the amount of the one or more underivatized docosanoic acid, tetracosanoic acid, and/or hexacosanoic acid in the sample from the amount of the one or more underivatized docosanoic acid, tetracosanoic acid, and/or hexacosanoic acid ions determined in step (b).
1 more element
Dependencies are inferred from the claim text.