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US 12,241,066 B2Granted
Gene therapy of the FAAH pseudogene
AssigneeUCL Business PLC
InventorsJames John Cox, Devjit Srivastava
Life of this patent
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Abstract
The present invention relates to analgesic treatments to reduce pain through use of an inhibitor of fatty-acid amide hydrolase pseudogene (FAAH-OUT).
Claims3
A method of treatment of nociceptive, neuropathic, inflammatory or idiopathic pain, comprising administering an effective amount of an inhibitor of fatty-acid amide hydrolase pseudogene (FAAH-OUT) to an individual with nociceptive, neuropathic, inflammatory or idiopathic pain, wherein FAAH-OUT is defined by SEQ ID NO:
- 5, and wherein the inhibitor is a guide RNA comprising a guide sequence that hybridizes to FAAH-OUT and targets a CRISPR-Cas enzyme to FAAH-OUT.
Dependencies are inferred from the claim text.