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US 12,240,973 B2Granted
Endoluminal device and polymer
AssigneeEndologix, Inc.
InventorsMehdi Durali, Lonnie Jones
Life of this patent
Estimating the term…
Abstract
Various embodiments relate to compositions for use in endoluminal devices and to methods of using compositions in endoluminal devices. The compositions include two parts, a first part including a first solution and a second part including a second solution, wherein the first solution comprises one or more pre-polymers, a non-aqueous solvent, a polymerization co-initiator or initiator and optionally one or more chain extenders and additives, and the second solution comprises a polymerization initiator or co-initiator, a non-aqueous solvent and optionally one or more chain extenders and additives.
Claims21
An organogel composition comprising two parts, a first part comprising a first solution and a second part comprising a second solution, wherein
- the first solution comprises one or more pre-polymers, a non-aqueous solvent, a polymerization co-initiator or initiator, and optionally one or more chain extenders and additives;
- and
- the second solution comprises a polymerization initiator or co-initiator, a non-aqueous solvent, and optionally one or more chain extenders and additives,
- wherein the first part and the second part are separate from each other,
- wherein the non-aqueous solvent of the first solution does not react with the one or more pre-polymers in the first solution,
- wherein the one or more pre-polymers comprises compounds having at least two functional groups selected from acrylate, methacrylate, and vinyl functional groups, the one or more pre-polymers selected from the group consisting of ethoxylated (3) bisphenol A diacrylate, ethoxylated (30) bisphenol A diacrylate (EBPADA), ethoxylated (9) trimethylolpropane triacrylate, ethoxylated (15) trimethylolpropane triacrylate, ethoxylated (20) trimethylolpropane triacrylate (PEG-T), propoxylated (3) trimethylolpropane triacrylate (PTMPTA), pentaerythritol triacrylate, ethoxylated (4) pentaerythritol tetraacrylate, pentaerythritol tetraacrylate, the methacrylic variants of the aforesaid acrylates, divinyl adipate, 1,4-dibutane diol divinyl ether, di and tri-ethylene glycol divinyl ether, allyl ether, diallyl maleate, trimethyl propane diallyl ether, and combinations thereof, and
- wherein a combination of the first part and second part
- exhibits a viscosity of from about 5 cP to about 100 cP, at 25° C., 30% solution, and
- forms an organogel exhibiting a static compressive modulus of from about 0.1 MPa to about 50 MPa, measured in accordance with ASTM D575-91, within a gel time of about 30 seconds to about 30 minutes.
6 more elements
An organogel composition comprising two parts, a first part comprising a first solution and a second part comprising a second solution, wherein
- the first solution comprises one or more pre-polymers, a non-aqueous solvent, a polymerization co-initiator or initiator, and optionally one or more chain extenders and additives;
- and
- the second solution comprises a polymerization initiator or co-initiator, a non-aqueous solvent, and optionally one or more chain extenders and additives,
- wherein the first part and the second part are separate from each other,
- wherein the non-aqueous solvent of the first solution does not react with the one or more pre-polymers in the first solution,
- wherein the one or more pre-polymers comprises compounds having at least two functional groups selected from acrylate, methacrylate, and vinyl functional groups, the one or more pre-polymers selected from the group consisting of ethoxylated (3) bisphenol A diacrylate, ethoxylated (30) bisphenol A diacrylate (EBPADA), ethoxylated (9) trimethylolpropane triacrylate, ethoxylated (15) trimethylolpropane triacrylate, ethoxylated (20) trimethylolpropane triacrylate (PEG-T), propoxylated (3) trimethylolpropane triacrylate (PTMPTA), pentaerythritol triacrylate, ethoxylated (4) pentaerythritol tetraacrylate, pentaerythritol tetraacrylate, the methacrylic variants of the aforesaid acrylates, divinyl adipate, 1,4-dibutane diol divinyl ether, di and tri-ethylene glycol divinyl ether, allyl ether, diallyl maleate, trimethyl propane diallyl ether, and combinations thereof,
- wherein the non-aqueous solvent includes aliphatic and/or aromatic solvents, the non-aqueous solvent selected from the group consisting of alcohols, aldehydes, amides, carbonates, ethers, esters, glycols, glycol ethers, glycol esters, hydrocarbons, ketones, sulfoxides, and vegetable oils, and
- wherein a combination of the first part and second part forms an organogel exhibiting a static compressive modulus of from about 0.1 MPa to about 50 MPa, measured in accordance with ASTM D575-91, within a gel time of about 30 seconds to about 30 minutes.
5 more elements
A method of forming an organogel comprising:
- contacting a first part of a composition and a second part of the composition, wherein
- the first part of the composition comprises a first solution comprising one or more pre-polymers, a non-aqueous solvent, a polymerization co-initiator or initiator, and optionally one or more chain extenders and additives;
- and
- the second part of the composition comprises a second solution comprising a polymerization initiator or co-initiator, a non-aqueous solvent, and optionally one or more chain extenders and additives,
- wherein the first part and second part are separate from each other prior to contacting,
- wherein the non-aqueous solvent of the first solution does not react with the one or more prepolymers in the first solution,
- wherein the one or more pre-polymers comprises compounds having at least two functional groups selected from acrylate, methacrylate, and vinyl functional groups, the one or more pre-polymers selected from the group consisting of ethoxylated (3) bisphenol A diacrylate, ethoxylated (30) bisphenol A diacrylate (EBPADA), ethoxylated (9) trimethylolpropane triacrylate, ethoxylated (15) trimethylolpropane triacrylate, ethoxylated (20) trimethylolpropane triacrylate (PEG-T), propoxylated (3) trimethylolpropane triacrylate (PTMPTA), pentaerythritol triacrylate, ethoxylated (4) pentaerythritol tetraacrylate, pentaerythritol tetraacrylate, the methacrylic variants of the aforesaid acrylates, divinyl adipate, 1,4-dibutane diol divinyl ether, di and tri-ethylene glycol divinyl ether, allyl ether, diallyl maleate, trimethyl propane diallyl ether, and combinations thereof;
- and
- initiating polymerization of the one or more pre-polymers to form the composition exhibiting a viscosity of from about 5 cP to about 100 cP, at 25° C., 30% solution, wherein the composition forms an organogel exhibiting a static compressive modulus of from about 0.1 MPa to about 50 MPa, measured in accordance with ASTM D575-91, within a gel time of about 30 seconds to about 30 minutes.
6 more elements
Dependencies are inferred from the claim text.