Devices and methods for nanofiber-based membrane fabrication

An electrospinning device, comprising:

• a glove comprising an electrically insulating material and configured to be worn on a hand of a user;
• a needleless spinneret disposed on a first surface of the glove and configured to produce a nanofiber-based film from a solution by electrospinning;
• a solution delivery unit disposed on the glove and configured to contain the solution;
• a solution delivery conduit connecting the solution delivery unit to the needleless spinneret;
• a solution flow control in operable communication with the solution delivery unit and configured to control at least one of a flow rate and a time of solution delivery from the solution delivery unit to the needleless spinneret during use;
• a voltage control portion configured to provide power to the electrospinning device;
• a plurality of lights disposed on the first surface of the glove;
• and
• a wrist support comprising a rigid material and disposed on at least the second surface of the glove,
• the solution flow control being disposed on a second surface of the glove opposite from the first surface,
• the solution being a polymer solution comprising at least one drug,
• the voltage control portion comprising exactly one battery configured to provide a voltage of no more than 1.4 Volts (V) to the electrospinning device,
• the solution delivery unit being disposable,
• the needleless spinneret comprising:
• a needless spinneret chamber configured to contain the solution;
• a plurality of conical spinneret nozzles on a bottom surface of the needleless spinneret;
• a plurality of fiber deposition boosters on the bottom surface of the needleless spinneret;
• and
• a solution flow control inlet coupled to the solution delivery conduit,
• the plurality of conical spinneret nozzles and the plurality of fiber deposition boosters being disposed such that lines of conical spinneret nozzles alternate with fiber deposition boosters in a circumferential direction around the bottom surface of the needleless spinneret, and
• the electrospinning device being configured to form a film from the solution at a flow rate in a range of from 0.07 nanoliters per hour (nl/h) to 0.8 nanoliters per minute (nl/min).