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US 12,234,264 B2Granted
Stabilized soluble pre-fusion RSV F proteins
AssigneeJanssen Vaccines & Prevention B.V.
InventorsAnders Krarup, Johannes Petrus Maria Langedijk
Life of this patent
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Abstract
Stable pre-fusion respiratory syncytial virus (RSV) F proteins (or fragment thereof) are described. Compositions containing the proteins and uses of the compositions for the prevention and/or treatment of RSV infection are also described.
Claims8
A recombinant polypeptide comprising F1 and F2 domains of a variant pre-fusion respiratory syncytial virus (RSV) Fusion (F) protein and a fibritin trimerization domain, wherein the recombinant polypeptide comprises the amino acid sequence of SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.