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US 12,234,207 B2Granted
Halo-(3-(phenylsulfonyl)prop-1-enyl)pyridine derivative and use thereof
AssigneeCureverse Incorporated
InventorsKi Duk Park, Ae Nim Pae, Sang Min Lim, Jong Hyun Park, Ji Won Choi, Siwon Kim, Hyeon Jeong Kim, Seul Ki Yeon
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Abstract
The present invention relates to a novel halo-(3-(phenylsulfonyl)prop-1-enyl)pyridine derivative or a pharmaceutically acceptable salt thereof; a preparation method thereof; and an Nrf2 activator and a pharmaceutical composition for preventing or treating diseases induced by a decrease in Nrf2 activity, both of which comprise the same as an active ingredient.
Claims20
A compound represented by Chemical Formula 1 below or a pharmaceutically acceptable salt thereof:
- wherein, in the Chemical Formula 1,
- R1 is a halogen,
- R2 is hydrogen or C1-4 alkyl,
- n is an integer of 1 to 5, and
- X is a halogen.
2 more elements
Dependencies are inferred from the claim text.