Back to results
US 12,228,565 B2Granted
Blood cell lysis compositions and uses thereof
AssigneeInstrumentation Laboratory Company
InventorsMiklos Erdosy, Hyoungsik Yim, Emily McDowell, Prasad V. A. Pamidi
Life of this patent
Estimating the term…
Abstract
An example blood cell lysis composition includes a buffer and a secondary alcohol ethoxylate at a concentration in the range of about 2.5 percent (%) to about 20% weight per volume (w/v). The secondary alcohol ethoxylate may include Tergitol™ TMN-100X or Tergitol™ 15-S-9. The composition may be configured to lyse at least 90% of blood cells in a blood sample.
Claims17
A blood cell lysis composition comprising:
- a buffer;
- and
- a secondary alcohol ethoxylate at a concentration between 9% weight per volume (w/v) and 20% w/V;
- wherein the secondary alcohol ethoxylate comprises one or more of:
- a first secondary alcohol ethoxylate having the following structural formula where x is 5, 7, 9, 11, 12, 13, 14, or 15,
- a second secondary alcohol ethoxylate having the following structural formula where n is 6, 10, 11, 12, 13, 14, or 15,
3 more elements
Dependencies are inferred from the claim text.