Glycophospholipid polymeric network and use thereof
AssigneeBausch & Lomb Incorporated
InventorsAlok Kumar Awasthi, James Anthony DiBella, Jr., Mark R. Mis, Alai Musleh, George L. Grobe, III
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Abstract
A biomedical device having a coating on a surface thereof, where the coating includes a glycophospholipid polymer which is a reaction product of one or more glycosaminoglycans and one or more phospholipids.
Claims20
A biomedical device having a coating on a surface thereof, the coating comprising a crosslinked glycophospholipid polymeric network comprising a reaction product of one or more glycosaminoglycans having one or more reactive functionality groups, one or more phospholipids having one or more reactive functionality groups and one or more first crosslinking agents, wherein the one or more first crosslinking agents comprise a bi- or polyfunctional crosslinking agent comprising two or more functional groups that are complementary to the one or more reactive functionality groups of the one or more glycosaminoglycans and the one or more phospholipids;
- wherein one of the two or more functional groups of the bi- or polyfunctional crosslinking agent is an epoxide functional group and a bond between the epoxide functional group of the bi- or polyfunctional crosslinking agent and at least one of the one or more reactive functionality groups of the one or more glycosaminoglycans is an ether bond.
Dependencies are inferred from the claim text.