Acinetobacter baumannii immunogenic protein and composition and application thereof

A method for protecting animals or humans from infection of Acinetobacter baumannii or a method for preventing and/or treating with diseases caused by Acinetobacter baumannii, which comprises the following steps:

• immunizing a non-human animal or a human with a biomaterial to achieve resistance to Acinetobacter baumannii infection, wherein the biomaterial is one of the following:
• 1) a protein consisting of 39 amino acids in the N-terminal α-helix part of the Ata protein transport functional domain of Acinetobacter baumannii;
• 2) a protein composition consisting of 39 amino acids in the N-terminal α-helix part of the Ata protein transport functional domain of Acinetobacter baumannii and an adjuvant protein or a protein fragment with adjuvant function;
• 3) a fusion protein consisting of 39 amino acids in the N-terminal α-helix part of the Ata protein transport functional domain of Acinetobacter baumannii and an adjuvant protein or a protein fragment with adjuvant function;
• wherein the amino acid sequence of said 39 amino acids in the N-terminal α-helix part of the Ata protein transport functional domain of Acinetobacter baumannii is shown as the amino acid residues 127-165 of SEQ ID NO:
• 2,
• wherein the fusion protein is any one of the following a)-c):
• a) the amino acid sequence consisting of the amino acid residues shown as SEQ ID NO:
• 2 in the sequence listing;
• b) a fusion protein obtained by attaching a tag to the N-terminal and/or C-terminal of the protein defined in a);
• and
• c) a protein whose amino acid sequence consists of the amino acid residues 20-165 of SEQ ID NO:
• 2 in the sequence listing.