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US 12,226,475 B2Granted
Treatment of insect bite hypersensitivity
AssigneeUniversitäT ZüRich
InventorsAntonia Fettelschoss, Martin Bachmann
Life of this patent
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Abstract
The present invention relates to compositions, immunogenic or vaccine compositions and pharmaceutical compositions for the prevention or treatment of insect bite 5 hypersensitivity of equine mammals, preferably of horses. Furthermore, the invention provides methods for preventing or treating insect bite hypersensitivity of equine mammals, preferably of horses.
Claims19
A composition comprising:
- (a) a core particle with at least one first attachment site;
- and
- (b) at least one antigen with at least one second attachment site, wherein said at least one antigen is an equine Interleukin-5 antigen (eIL-5 antigen), wherein said eIL-5 antigen comprises a protein with the amino acid sequence selected from SEQ ID NO:1 or a protein with an amino acid sequence of at least 90% amino acid sequence identity with SEQ ID NO:1;
- wherein (a) and (b) are linked through said at least one first and said at least one second attachment site via at least one non-peptide covalent bond, and wherein said first attachment site is an amino group and said second attachment site is a sulfhydryl group.
1 more element
Dependencies are inferred from the claim text.