# US 12,222,269 B2 · Blood collection tube for measuring blood viscosity, blood viscosity measurement device, and sealed pack of blood collection tube for measuring blood viscosity

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- Number: US 12,222,269 B2
- Document ID: US12222269B2
- Status: Granted
- Kind: B2
- Application number: 17/789,078
- Filed: 2019-12-27
- Published: 2023-02-09
- Granted: 2025-02-11
- Earliest claimed: 2019-12-27
- Assignees: Medical Univerisity of Vienna; Kansai University; Taisei Kako Co., Ltd.; Asahi Group Holdings, Ltd.
- Applicants: Medical University of Vienna; Kansai University; Taisei Kako Co., Ltd.; Asahi Group Holdings, Ltd.
- Inventors: Roberto Plasenzotti; Bruno Karl Podesser; Hideki Yamamoto; Yusuke Negi; Takafumi Yabuta; Hidenari Nishikura; Eiji Tamura; Kimito Kawamura
- Web page: https://patentgrep.com/patent/US12222269B2

## CPC

- G01N 11/12: by measuring rising or falling speed of the body; by measuring penetration of wedged gauges (G01N11/16 takes precedence)
- A61B 5/15003: {for venous or arterial blood}
- A61B 5/150351: {Caps, stoppers or lids for sealing or closing a blood collection vessel or container, e.g. a test-tube or syringe barrel}
- B01L 3/50825: {Closing or opening means, corks, bungs}
- G01N 33/49: Blood {(chemical methods for determining blood cell populations G01N33/5094; chemical analysis of blood groups or blood types G01N33/80)}
- A61B 5/150389: {Hollow piercing elements, e.g. canulas, needles, for piercing the skin}
- A61B 5/150473: {Double-ended needles, e.g. used with pre-evacuated sampling tubes (hollow piercing element tip design A61B5/150396)}
- A61B 5/154: {Devices} using pre-evacuated means
- A61B 5/157: {Devices} characterised by integrated means for measuring characteristics of blood
- B01L 2300/041: Connecting closures to device or container
- B01L 2300/046: Function or devices integrated in the closure
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- B01L: CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE

## Abstract

A blood-viscosity measurement blood collection tube includes a bottomed tube provided with an opening at one end in a length direction and a bottom at the other in the length direction, and a sealing plug. The sealing plug includes a sealing part fitted in the opening of the bottomed tube in a hermetically sealed state, a cap part, and a thin connecting part. The sealing part includes a vertically penetrated insertion hole. The sealing part of the sealing plug is fitted in the opening of the bottomed tube, and an inner space of the bottomed tube is in a negative pressure state. The cap part is configured to be removed from the sealing plug by breaking the connecting part with an external force applied to the cap part, and the insertion hole is exposed at an upper surface of the sealing part when the cap part has been removed.

## Claims

### Claim 1

A blood-viscosity measurement blood collection tube, comprising:
a bottomed tube provided with an opening at one end in a length direction and a bottom at the other end in the length direction; and
a sealing plug,
wherein the sealing plug is provided with a sealing part capable of being fitted in the opening of the bottomed tube in a hermetically sealed state, a cap part, and a thin connecting part connecting the cap part and the sealing part,
wherein the sealing part is provided with a vertically penetrated insertion hole,
wherein the sealing part of the sealing plug is fitted in the opening of the bottomed tube, and an inner space of the bottomed tube is in a negative pressure state, and
wherein the cap part is configured to be removed from the sealing plug by breaking the connecting part with an external force applied to the cap part, and the insertion hole is exposed at an upper surface of the sealing part when the cap part is removed.

### Claim 2 (depends on 1)

The blood-viscosity measurement blood collection tube as recited in claim 1, further comprising:
a guide tube communicated with the insertion hole, the guide tube being secured to the sealing part in a downwardly extended manner.

### Claim 3 (depends on 1)

The blood-viscosity measurement blood collection tube as recited in claim 1,
wherein the guide tube is provided with one or a plurality of apertures or slits formed on a side surface of the guide tube.

### Claim 4 (depends on 1)

A blood-viscosity measurement device comprising:
a viscosity measurement falling body;
a blood-viscosity measurement blood collection tube as recited in claim 1; and
a detector configured to detect a fall terminal velocity of a viscosity measurement falling body which is falling in the blood collection tube.

### Claim 5 (depends on 1)

A blood-viscosity measurement blood collection tube sealed pack, comprising:
the blood-viscosity measurement blood collection tube as recited in claim 1; and
a vacuum pack in which the blood-viscosity measurement blood collection tube is hermetically sealed in a vacuumed state.