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US 12,221,406 B2Granted
Compounds as NLRP3 inflammasome inhibitors and compositions and uses thereof
AssigneeVirginia Commonwealth University
InventorShijun Zhang
Life of this patent
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Abstract
Scaffold compounds are used to design small molecule compounds and structure-activity relationship studies identify inhibitors of inflammation. Methods include pharmaceutical compositions of the small molecule compounds to inhibit, prevent and treat diseases and conditions associated with inflammation, including multiple sclerosis, Alzheimer's disease, acute myocardial infarction, traumatic brain injury and autoinflammatory diseases.
Claims1
A compound having the chemical structure of
- and pharmaceutically acceptable salts, solvates, or hydrates thereof.
Dependencies are inferred from the claim text.