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US 12,220,448 B2Granted
Method of treating pathogenic bacterial infectious diseases
AssigneeKyungpook National University Industry-Academic Cooperation Foundation
InventorsJung Min Kim, Jong Sook Jin, Shukho Kim
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Abstract
The invention relates to a method of preventing or treating pathogenic bacterial infectious diseases by providing a pharmaceutical composition comprising a LysSAP26 protein, wherein the LysSAP26 protein is a recombinant protein composed of an amino acid sequence derived from the bacteriophage genome and has the amino acid sequence set forth in SEQ ID NO: 1 as an active ingredient, and administering the pharmaceutical composition to a subject.
Claims2
A method of treating a pathogenic bacterial infectious disease, comprising:
- administering to a subject a pharmaceutical composition comprising a LysSAP26 protein,
- wherein the LysSAP26 protein has the amino acid sequence set forth in SEQ ID NO:
- 1 and a pharmaceutically acceptable carrier,
- wherein the pathogenic bacterial infectious disease is caused by carbapenem-resistant Acinetobacter baumannii (CRAB), and is selected from the group consisting of sepsis, impetigo, purulent disease, and wound infection, and
- wherein the LysSAP26 protein is obtained from a bacteriophage SAP26 of Siphoviridae deposited as Accession Number KCTC 11665BP.
2 more elements
Dependencies are inferred from the claim text.