# US 12,215,097 B2 · Derivatives of substituted morpholines and uses thereof

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 12,215,097 B2
- Document ID: US12215097B2
- Status: Granted
- Kind: B2
- Application number: 18/416,455
- Filed: 2024-01-18
- Published: 2024-06-06
- Granted: 2025-02-04
- Earliest claimed: 2021-03-18
- Assignees: Supernus Pharmaceuticals, Inc.
- Applicants: Supernus Pharmaceuticals, Inc.
- Inventors: Janak Khimchand Padia
- Web page: https://patentgrep.com/patent/US12215097B2

## CPC

- C07D 413/12: linked by a chain containing hetero atoms as chain links
- C07D 265/30: not condensed with other rings
- C07D 413/14: containing three or more hetero rings
- C07D: HETEROCYCLIC COMPOUNDS (macromolecular compounds C08)

## Abstract

A compound of Formula I includes a stereoisomer thereof and/or a salt thereof; wherein R1 is a substituted alkane group, a heterocylic group, or a pyridine group; X is hydrogen, a halogen, an amino acid residue, a substituted amino acid residue, an alkyl group, or an ester. Such compounds may be used in pharmaceutical compositions and for the treatment of central nervous system (CNS) disorders:

## Claims

### Claim 1

A stereoisomer of a compound of the formula:
or a salt thereof.

### Claim 2 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 3 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 4 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 5 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 6 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 7 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 8 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 9 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 10 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 11 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 12 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 13 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 14 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 15 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 16 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 17 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 18 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 19 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 20 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 21 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 22 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 23 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 24 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 25 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 26 (depends on 1)

The stereoisomer of claim 1 having the structure:

### Claim 27 (depends on 1)

The stereoisomer of claim 1 having the structure: