# US 12,214,175 B2 · Electronic-ink label for a drug delivery device

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 12,214,175 B2
- Document ID: US12214175B2
- Status: Granted
- Kind: B2
- Application number: 17/294,533
- Filed: 2019-11-19
- Published: 2022-01-20
- Granted: 2025-02-04
- Earliest claimed: 2018-11-23
- Assignees: Sanofi
- Applicants: Sanofi
- Inventors: Maurice Toporek
- Web page: https://patentgrep.com/patent/US12214175B2

## CPC

- A61M 5/31: Details
- A61M 5/31568: {Means keeping track of the total dose administered, e.g. since the cartridge was inserted}
- A61M 5/20: Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically (A61M5/142 takes precedence)
- A61M 5/31511: {Piston or piston-rod constructions, e.g. connection of piston with piston-rod (A61M5/5066 takes precedence)}
- A61M 2005/3126: {related to dosing}
- A61M 2205/3317: Electromagnetic, inductive or dielectric measuring means
- A61M 2205/3553: remote, e.g. between patient's home and doctor's office
- A61M 2205/502: User interfaces, e.g. screens or keyboards
- A61M 2205/583: by visual feedback
- A61M 2205/8206: battery-operated
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

Described is an indication system for a drug delivery device, including a component moveable with respect to a housing during operation of the drug delivery device, an electric circuit having an electrical property, and an electronic-ink label configured to be disposed on the exterior of the housing and in contact with the electric circuit. The electric circuit is operatively coupled to the moveable component to modify the electrical property based on a position of the moveable component such that the electrical property is an indication of the position of the moveable component. The electronic ink label includes printed electronics arranged to be in communication with the electric circuit and configured to display a visual indication related to the position of the moveable component in response to the electrical property. In some instances, the position of the moveable component indicates a dose set or dispensed from the drug delivery device.

## Claims

### Claim 1

An indication system for use in a drug delivery device, the indication system comprising:
a housing;
a moveable component configured to move with respect to the housing during operation of the drug delivery device;
an electric circuit having an electrical property, the electric circuit comprising:
an electrical component operatively coupled to the moveable component and configured to modify the electrical property based on a position of the moveable component, such that the electrical property of the electric circuit is an indication of the position of the moveable component, and
an electric contact on an exterior of the housing; and
an electronic-ink label configured to be disposed on the exterior of the housing, the electronic-ink label comprising:
printed electronics arranged to be in electrical communication with the electric circuit via the electric contact and configured to display a visual indication related to the position of the moveable component in response to the electrical property of the electric circuit,
wherein the electrical component comprises:
a first component comprising:
a track spanning at least a portion of a length of the first component, and
first and second conductors, each extending continuously along an entire length of the track, the entire length spanning between a distal most end and a proximal most end of the track; and
a second component that is conductive and moveable with respect to the first component along the track, the second component contacting the first and second conductors, wherein the electrical property is proportional to a position of the second component along the length of the first component,
wherein the moveable component of the drug delivery device comprises the first component or the second component, and
wherein the position of the second component with respect to the first component is changed during a dose setting operation or a dose dispensing operation of the drug delivery device.

### Claim 2 (depends on 1)

The indication system of claim 1, wherein the moveable component is configured to move between a plurality of possible positions with respect to the housing, and wherein each of the plurality of possible positions of the moveable component defines a different value of the electrical property of the electric circuit, such that each value of the electrical property is an indication of a different position of the moveable component.

### Claim 3 (depends on 1)

The indication system of claim 1, wherein the position of the moveable component corresponds to an amount of medicament inside a medicament container or a position of a stopper inside the medicament container.

### Claim 4 (depends on 1)

The indication system of claim 1, wherein the electrical property is one or more of the following: capacitance, inductance, or resistance.

### Claim 5 (depends on 1)

The indication system of claim 1, wherein the electronic-ink label comprises an outer surface configured to display the visual indication and an inner surface comprising corresponding electrical contacts arranged to contact the electrical contact of the housing, and wherein the inner surface is configured to be secured to the exterior of the housing via an adhesive.

### Claim 6 (depends on 1)

The indication system of claim 1, comprising a dose memory mechanism having the moveable component, and wherein the position of the moveable component corresponds to a total dose of medicament remaining in the drug delivery device, and wherein the visual indication corresponds to the total dose of medicament remaining in the drug delivery device.

### Claim 7 (depends on 1)

The indication system of claim 1, wherein the first component is a threaded sleeve configured to move helically with respect to the housing during a dose setting operation, and wherein the second component is a thread insert carried by the housing, wherein the moveable component is the threaded sleeve and the visual indication corresponds to a dose set during the dose setting operation.

### Claim 8 (depends on 1)

The indication system of claim 1, wherein the first component is a leadscrew configured to move helically with respect to the housing during a dose dispensing operation of the drug delivery device to translate a stopper into a cartridge of the drug delivery device, wherein the second component comprises a bearing nut carried by the housing, and wherein the moveable component is the leadscrew and the visual indication corresponds to the position of the stopper in the cartridge.

### Claim 9 (depends on 1)

The indication system of claim 1, wherein the first component is a threaded plunger rod, and the second component is a last dose nut configured to thread along a drive sleeve during the dose setting operation, and wherein the moveable component is the last dose nut and the visual indication corresponds to a dose remaining in the drug delivery device.

### Claim 10 (depends on 1)

The indication system of claim 1, wherein the electronic-ink label comprises a battery for providing power to the printed electronics.

### Claim 11 (depends on 1)

The indication system of claim 1, wherein the electronic-ink label comprises an outer surface comprising a display for showing the visual indication.

### Claim 12 (depends on 1)

The indication system of claim 1, wherein the electronic-ink label comprises an RFID module configured to transmit a wireless signal related to the position of the moveable component in response to the electrical property of the electric circuit.