# US 12,214,155 B2 · Fluid injector system volume compensation system and method > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,214,155 B2 - Document ID: US12214155B2 - Status: Granted - Kind: B2 - Application number: 18/048,931 - Filed: 2022-10-24 - Published: 2023-03-02 - Granted: 2025-02-04 - Earliest claimed: 2017-08-31 - Assignees: Bayer HealthCare LLC - Applicants: Bayer Healthcare LLC - Inventors: Michael Mcdermott; Michael Spohn; William Barone; Chelsea Marsh - Web page: https://patentgrep.com/patent/US12214155B2 ## CPC - A61M 5/007: {for contrast media} - A61M 5/1408: {in parallel, e.g. by manifolds or with sequencing valves} - A61M 5/14228: {with linear peristaltic action, i.e. comprising at least three pressurising members or a helical member} - A61M 5/1452: {pressurised by means of pistons} - A61M 5/14546: {Front-loading type injectors} - A61M 5/14586: {pressurised by means of a flexible diaphragm} - A61M 5/148: flexible (A61M5/155 takes precedence) - A61M 5/168: Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters - A61M 5/1684: {by detecting the amount of infusate remaining, e.g. signalling end of infusion} - A61M 5/16854: {by monitoring line pressure} - A61M 5/16877: {Passive flow controllers; Devices for setting a flow rate (clamp-type valves A61M39/28)} - A61M 5/16881: {Regulating valves} - A61M 5/172: electrical or electronic - A61M 2005/14208: {with a programmable infusion control system, characterised by the infusion program} - A61M 2005/14553: {comprising a pressure jacket} - A61M 2205/3331: Pressure; Flow - A61M 2205/3362: with minimised length of fluid lines; Taking into account the elastic expansion of fluid lines to increase accuracy - A61M 2205/3389: Continuous level detection (A61M2205/3393 takes precedence) - A61M 2205/50: with microprocessors or computers - A61M 2205/702: automatically during use - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract A system and method for correcting a volume of fluid delivered by a fluid injector during an injection procedure is described. The method included determining and compensating for a volume factor associated with compliance of the fluid injector system and correcting for the volume by one of over-driving the distance that the drive member travels in a fluid reservoir, under-driving the distance that the drive member travels in the fluid reservoir, or lengthening or shortening a fluid delivery time. ## Claims ### Claim 1 A method for correcting a volume of fluid delivered by a fluid injector system during an injection procedure, the method comprising: determining a fluid volume of a first fluid in at least one fluid reservoir of the fluid injector system; determining a pressure at which a first programmed volume of the first fluid is to be injected; calculating a first system volume compliance of the at least one fluid reservoir, one or more fluid injector mechanical components associated with the fluid injector system, and one or more tubing system components based on: the volume of the first fluid, the pressure of the first fluid, and one or more correction factors based on capacitance characteristics of the at least one fluid reservoir and one or more tubing system components, fluid properties of the first fluid, and a component slack of the one or more fluid injector mechanical components associated with the fluid injector system; calculating a first volume compliance factor of the first fluid in the at least one fluid reservoir based on the first programmed volume of the first fluid and the calculated first system volume compliance; and compensating for the first volume compliance factor to deliver the first programmed volume by one of: over-driving a distance that a first drive member travels in the at least one fluid reservoir, under-driving the distance that the first drive member travels in the at least one fluid reservoir, increasing a delivery time of the first fluid in the at least one fluid reservoir, and decreasing the delivery time of the first fluid in the at least one fluid reservoir. ### Claim 2 (depends on 1) The method of claim 1, wherein the at least one fluid reservoir comprises at least one first fluid reservoir containing the first fluid and at least one second fluid reservoir containing a second fluid, wherein the method further comprises: determining a fluid volume of the second fluid in the at least one second fluid reservoir of the fluid injector system; determining a second pressure at which a second programmed volume of the second fluid is to be injected; calculating a second system volume compliance of the at least one second fluid reservoir, the one or more fluid injector mechanical components associated with the fluid injector system, and the one or more tubing system components based on: the volume of the second fluid, the pressure of the second fluid, and one or more correction factors based on capacitance characteristics of the at least one second reservoir and one or more tubing system components, fluid properties of the second fluid, and the component slack of the one or more fluid injector mechanical components associated with the fluid injector system; calculating a second volume compliance factor of the second fluid in the at least one second fluid reservoir based on the second programmed volume of the second fluid and the calculated second system volume compliance; and compensating for the second volume compliance factor to deliver the second programmed volume by one of: over-driving a distance that a second drive member travels in the at least one second fluid reservoir, under-driving the distance that the second drive member travels in the at least one second fluid reservoir, increasing a delivery time of the second fluid in the at least one second fluid reservoir, and decreasing the delivery time of the second fluid in the at least one second fluid reservoir. ### Claim 3 (depends on 1) The method of claim 1, further comprising the step of determining whether the at least one fluid reservoir contains at least a volume of the first fluid corresponding to the programmed volume plus an amount of the first fluid equal to the calculated system volume compliance of the at least one fluid reservoir. ### Claim 4 (depends on 2) The method of claim 2, wherein the at least one first fluid reservoir and the at least one second fluid reservoir are independently selected from a group consisting of a syringe, a rolling diaphragm syringe, a peristaltic pump, and a compressible bag. ### Claim 5 (depends on 2) The method of claim 2, wherein at least one of the at least one first fluid reservoir and the at least one second fluid reservoir is a syringe. ### Claim 6 (depends on 5) The method of claim 5, wherein the syringe comprises a plunger operatively connected to a piston selected from a linear actuated piston and a motor driven piston. ### Claim 7 (depends on 2) The method of claim 2, wherein at least one of the at least one first fluid reservoir and the at least one second fluid reservoir is a rolling diaphragm syringe. ### Claim 8 (depends on 7) The method of claim 7, wherein a proximal end of the rolling diaphragm syringe is operatively connected to a piston selected from a linear actuated piston and a motor driven piston. ### Claim 9 (depends on 1) The method of claim 1, wherein the first system volume compliance is calculated according to Equation (1): C1=A1·V1+B1·P1+O1 (1) where C1 is the first system volume compliance of the at least one fluid reservoir, A1 is a position scalar of the at least one fluid reservoir, V1 is available volume of the at least one fluid reservoir, B1 is a pressure constant of the at least one fluid reservoir, P1 is a pressure of fluid within the at least one fluid reservoir, and O1 is the compensation factor of the at least one fluid reservoir. ### Claim 10 (depends on 2) The method of claim 2, wherein the second system volume compliance is calculated according to Equation (2): C2=A2·V2+B2·P2+O2 (2) where C2 is the second system volume compliance of the at least one second fluid reservoir, A2 is a position scalar of the at least one second fluid reservoir, V2 is available volume of the at least one second fluid reservoir, B2 is a pressure constant of the at least one second fluid reservoir, P2 is a pressure of fluid within the at least one second fluid reservoir, and O2 is the compensation factor of the at least one second fluid reservoir. ### Claim 11 (depends on 8) The method of claim 8, wherein the first volume compliance factor is calculated according to Equation (3): VC1=PV1+C1 (3) where VC1 is the first volume compliance factor of the first fluid in the at least one fluid reservoir, PV1 is the programmed volume of the first fluid, and C1 is the first system volume compliance of the at least one fluid reservoir; and wherein the second volume compliance factor is calculated according to Equation (4): VC2=PV2+C2 (4) where VC2 is the second volume compliance factor of the second fluid in the at least one second fluid reservoir, PV2 is the programmed volume of the second fluid, and C2 is the second system volume compliance of the at least one second fluid reservoir. ### Claim 12 (depends on 1) The method of claim 1, wherein compensating for the first volume compliance factor the at least one fluid reservoir comprises: over-driving the distance that the first drive member travels in the at least one fluid reservoir; and injecting an additional volume of the first fluid equal to the calculated first volume compliance factor. ### Claim 13 (depends on 12) The method of claim 12, further comprising closing a valve to fluidly isolate the at least one fluid reservoir from the patient after injecting the additional volume of the first fluid. ### Claim 14 (depends on 1) The method of claim 1, wherein compensating for the second volume compliance factor the at least one second fluid reservoir comprises: over-driving the distance that the second drive member travels in the at least one second fluid reservoir; and injecting an additional volume of the second fluid equal to the calculated second volume compliance factor. ### Claim 15 (depends on 14) The method of claim 14, further comprising closing a valve to fluidly isolate the at least one second fluid reservoir from the patient after injecting the additional volume of the second fluid. ### Claim 16 (depends on 1) The method of claim 1, further comprising reporting to a user a value corresponding to corrected volume of the first fluid being delivered to a patient from the at least one fluid reservoir, wherein the corrected volume accounts for the first programmed volume and the first system volume compliance. ### Claim 17 A fluid delivery system comprising: a fluid injector; at least one first fluid reservoir configured to contain a first fluid; at least one first drive member configured to drive the first fluid from the at least one first fluid reservoir; and a controller in operable communication with the at least one first drive member, wherein the controller comprises computer readable memory containing instructions that, when executed by the controller, cause the controller to: determine a fluid volume of the first fluid in at least one first fluid reservoir; determine a pressure at which a first programmed volume of the first fluid is to be injected; calculate a first system volume compliance of the at least one first fluid reservoir, one or more fluid injector mechanical components associated with the fluid injector, and one or more tubing system components based on: the volume of the first fluid, the pressure of the first fluid, and one or more correction factors based on capacitance characteristics of the at least one first fluid reservoir and one or more tubing system components, fluid properties of the first fluid, and a component slack of the one or more fluid injector mechanical components associated with the fluid injector; calculate a first volume compliance factor of the first fluid in the at least one first fluid reservoir based on the first programmed volume of the first fluid and the calculated first system volume compliance; and compensate for the first volume compliance factor to deliver the first programmed volume by one of: over-driving a distance that the at least one first drive member travels in the at least one fluid reservoir, under-driving the distance that the at least one first drive member travels in the at least one fluid reservoir, increasing a delivery time of the first fluid in the at least one fluid reservoir, and decreasing the delivery time of the first fluid in the at least one fluid reservoir. ### Claim 18 (depends on 17) The fluid delivery system of claim 17, wherein the controller is configured to calculate the first system volume compliance volume according to Equation (1): C1=A1·V1+B1·P1+O1 (1) where C1 is the first system volume compliance of the at least one first fluid reservoir, A1 is a position scalar of the at least one first fluid reservoir, V1 is available volume of the at least one fluid reservoir, B1 is a pressure constant of the at least one first fluid reservoir, P1 is a pressure of fluid within the at least one first fluid reservoir, and O1 is the compensation factor of the at least one first fluid reservoir. ### Claim 19 (depends on 17) The fluid delivery system of claim 17, wherein the computer readable memory containing further instructions that, when executed by the controller, causes the controller to compensate for the first volume compliance factor by: over-driving the distance that the at least one first drive member travels in the at least one first fluid reservoir; and injecting an additional volume of the first fluid equal to the calculated first volume compliance factor. ### Claim 20 (depends on 17) The fluid delivery system of claim 17, wherein the computer readable memory containing further instructions that, when executed by the controller, causes the controller to compensate for the first volume compliance factor by: increasing the delivery time of the first fluid in the at least one first fluid reservoir by an amount sufficient to deliver an additional volume of the first fluid equal to the calculated first volume compliance factor.