# US 12,214,064 B2 · Alcohol based sanitizer with improved dermal compatibility and feel

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- Number: US 12,214,064 B2
- Document ID: US12214064B2
- Status: Granted
- Kind: B2
- Application number: 17/822,039
- Filed: 2022-08-24
- Published: 2023-01-05
- Granted: 2025-02-04
- Earliest claimed: 2013-06-06
- Assignees: Ecolab USA Inc.
- Applicants: Ecolab USA Inc.
- Inventors: Joseph R. Wegner; Cheryl A. Littau
- Web page: https://patentgrep.com/patent/US12214064B2

## CPC

- A61K 8/34: Alcohols
- A61K 8/042: {Gels}
- A61K 8/345: {containing more than one hydroxy group}
- A61K 8/365: Hydroxycarboxylic acids; Ketocarboxylic acids
- A61K 8/37: Esters of carboxylic acids
- A61K 8/375: {the alcohol moiety containing more than one hydroxy group}
- A61K 8/44: Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K 8/4913: {having five membered rings, e.g. pyrrolidone carboxylic acid}
- A61K 8/4926: {having six membered rings}
- A61K 8/678: {Tocopherol, i.e. vitamin E}
- A61K 8/891: saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
- A61K 8/893: modified by an alkoxy or aryloxy group, e.g. behenoxy dimethicone or stearoxy dimethicone
- A61P 17/00: Drugs for dermatological disorders
- A61Q 17/005: {Antimicrobial preparations}
- A61Q 19/10: Washing or bathing preparations
- A61K 31/045: Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K 31/455: Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
- A61K 2800/592: Mixtures of compounds complementing their respective functions
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

Applicants have identified a critical skin benefit package that can be used in liquid alcohol sanitizing compositions that provides lower amounts of skin conditioners in combination with a specific ratio of different emollients that provide improved skin health with chronic repeated use. The package also provides improved skin feel with without a tacky residue upon drying.

## Claims

### Claim 1

A liquid skin sanitizing composition comprising:
a) one or more skin conditioners;
b) a medium spreading emollient
c) a low spreading emollient,
d) a linear or branched C1 to C6 alcohol; and
e) water
wherein the composition does not have a gritty texture when applied to the skin.

### Claim 2 (depends on 1)

The liquid skin sanitizing composition of claim 1 wherein said C1 to C6 alcohol is in an amount of from about 50 wt. % to about 90 wt. % of said composition.

### Claim 3 (depends on 1)

The liquid skin sanitizing composition of claim 1, wherein said one or more skin conditioners total no more than about 3 wt. % of said composition.

### Claim 4 (depends on 1)

The liquid skin sanitizing composition of claim 1, wherein said one or more skin conditioners total no more than about 2 wt. % of said composition.

### Claim 5 (depends on 1)

The liquid skin sanitizing composition of claim 1, wherein said one or more skin conditioners total no more than about 1 wt. % of said composition.

### Claim 6 (depends on 1)

The liquid skin sanitizing composition of claim 1 wherein each conditioner is present in an amount of no more than 1 wt. % of said composition.

### Claim 7 (depends on 1)

The liquid skin sanitizing composition of claim 1 wherein each conditioner is present in an amount of no more than 0.8 wt. % of said composition.

### Claim 8 (depends on 1)

The liquid skin sanitizing composition of claim 1 wherein each conditioner is present in an amount of no more than 0.5 wt. % of said composition.

### Claim 9 (depends on 1)

The liquid skin sanitizing composition of claim 1 further comprising a high spreading emollient, wherein a ratio of high spreading emollient to medium spreading emollient is about 1:3 by weight.

### Claim 10 (depends on 1)

The liquid skin sanitizing composition of claim 1 wherein said medium spreading emollient includes one or more of: capric/caprylic triglyceride, C12-15 alkyl benzoate, capric triglyceride, caprylic triglyceride, isopropyl myristrate, isopropyl palmitate, octyldodecanol, decyl oleate, cocoglycerides, ethylhexyl stearate, ceteraryl isononanoate, cetearyl ethyhexanonate, decyl cocoate, cetyl dimethicone, ethylhexyl palmitate, PPG-11 stearyl ether, PPG-15 stearyl ether, Dimethicone fluid (10-20 cst), and PPG-14 butyl ether.

### Claim 11 (depends on 9)

The liquid skin sanitizing composition of claim 9 wherein said high spreading emollient includes one or more of dicaprylyl carbonate, dibutyl adipate, hexyl laurate, dicaprylyl ether, propylheptyl caprylate, 4-10 centistoke silicone oil, D4, 5, or 6 cyclic siloxane, isocetyl palmitate, hydrogenated polyisobutene, and diethylhexylcarbonate.

### Claim 12 (depends on 1)

The liquid skin sanitizing composition of claim 1 wherein said composition is in the form of a water thin liquid, a gel, an emulsion, or an aerosol foam.

### Claim 13 (depends on 1)

A method of sanitizing skin comprising:
applying the liquid skin sanitizer of claim 1 to a skin surface; and thereafter allowing said sanitizer to dry.

### Claim 14 (depends on 13)

The method of claim 13 wherein said steps of applying and drying are repeated from about 20 to 100 times a day.

### Claim 15 (depends on 13)

The method of claim 13 wherein said skin does not feel sticky or tacky upon drying.

### Claim 16 (depends on 13)

The method of claim 13 wherein said dry skin is easily gloved.

### Claim 17 (depends on 14)

The method of claim 14 wherein said sanitized skin has improved health and moisture compared to non-treated skin that is sanitized from about 20 to 100 times a day.

### Claim 18

A liquid skin sanitizing composition comprising:
a) one or more skin conditioners;
b) a medium spreading emollient
c) a low spreading emollient,
d) a linear or branched C1 to C6 alcohol;
e) water
wherein said one or more skin conditioners are present in an amount of no more than 0.5 wt. % each and further wherein said total skin conditioner component comprises no more than 1 wt. % of said sanitizing composition, and
wherein the composition does not have a gritty texture when applied to the skin.

### Claim 19 (depends on 18)

The liquid skin sanitizing composition of claim 18 wherein said skin conditioner is alkyl benzoate, myristyl myristate, cetyl myristate, gelatin, carboxylic acid, lactic acid, glyceryl dioleate, methyl laurate, PPG-9 laurate, lauryl lactate, allantoin, octyl palmitate, lanolin, propylene glycol, butylene glycol, ethylene glycol, caprylyl glycol, monobutyl ether, glycerine, a fatty acid, proline, almond oil, mineral oil, canola oil, sesame oil, soybean oil, pyrrolidine, wheat germ, hydrolyzed wheat protein, hydrolyzed oat protein, hydrolyzed collagen, corn, peanut and olive oil, isopropyl myristate, myristyl alcohol, aloe vera, algae extract, gluconic acid, hydrolyzed silk protein, 1,3-propane diol, Vitamin E, nicotinamide stearyl alcohol, isopropyl palmitate, sorbitol, amino acid complexes, panthenol, dihydroxypropyltrimonium chloride, quaternized hydrolyzed protein such as collagen, oat, wheat, inositol, fructose, sucrose, hydrolyzed plant proteins, seaweed extract, polyethylene glycol, ammonium lactate, sodium hyaluronate, betaine, cyclic peptides, hydroxyethyl urea, agarose, urea, sodium PCA, arginine PCA, fructose, glucose, glutamic acid, glycerine, honey, lactose, maltose, polyethylene glycol, sorbitol, petrolatum, shea butter, avocado oil, balm mint oil, cod liver oil, mineral oil, trimyristin, stearyl stearate, synthetic wax, ethyl hexylglycerin, cholesterol, cystine, hyaluronic acid, keratin, lecithin, egg yolk, glycine, PPG-12, polyquaternium-11, behentrimonium chloride, dihydroxypropyl PEG-5 linoleammonium chloride, glycerol oleate, PEG-7 glyceryl cocoate, cocoglucoside, PEG-200 hydrogenated glyceryl palmate, panthenol, retinol, salicylic acid, vegetable oil, methyl gluceth-10, methyl gluceth-20, an ethoxylated derivative of glycereth-26, ethoxylated shea butter, bisabolol, panthenol or a combination thereof.

### Claim 20 (depends on 18)

The liquid skin sanitizing composition of claim 18 wherein said composition is in the form of a water thin liquid, a gel, an emulsion, a non-aerosol foam or an aerosol foam.
