# US 12,214,063 B2 · Peroxymonosulfate whitening strips

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- Number: US 12,214,063 B2
- Document ID: US12214063B2
- Status: Granted
- Kind: B2
- Application number: 17/675,285
- Filed: 2022-02-18
- Published: 2022-08-25
- Granted: 2025-02-04
- Earliest claimed: 2021-02-19
- Assignees: Colgate-Palmolive Company
- Applicants: Colgate-Palmolive Company
- Inventors: Cajetan Dogo-Isonagie; Suman Chopra; Xiang Chen
- Web page: https://patentgrep.com/patent/US12214063B2

## CPC

- A61K 8/0216: {Solid or semisolid forms}
- A61K 8/0237: {Striped compositions}
- A61C 19/066: {Bleaching devices; Whitening agent applicators for teeth, e.g. trays or strips}
- A61K 8/22: Peroxides; Oxygen; Ozone
- A61K 8/23: Sulfur; Selenium; Tellurium; Compounds thereof
- A61K 8/24: Phosphorous; Compounds thereof
- A61K 8/8147: {Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers}
- A61K 8/8176: {Homopolymers of N-vinyl-pyrrolidones. Compositions of derivatives of such polymers}
- A61K 8/8182: {Copolymers of vinyl-pyrrolidones. Compositions of derivatives of such polymers}
- A61K 8/86: Polyethers
- A61Q 11/00: Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- A61K 2800/30: Characterized by the absence of a particular group of ingredients
- A61K 2800/594: Mixtures of polymers
- A61K 2800/87: Application Devices; Containers; Packaging
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61C: DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE (non-driven toothbrushes A46B; {tongue scrapers A61B17/24;} preparations for dentistry A61K6/00; preparations for cleaning the teeth or mouth A61K8/00, A61Q11/00)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

The present disclosure provides a tooth whitening strip comprising a hydratable adhesive film comprising an inorganic salt of peroxymonosulfate, preferably an alkali metal salt or alkaline earth metal salt, or mixtures thereof, and methods of using the same.

## Claims

### Claim 1

A tooth whitening strip comprising:
a hydratable adhesive film consisting of:
from about 60 to about 90%, by weight, of water-soluble or water-swellable polymers, the water-soluble or water-swellable polymers consisting of a polyvinylpyrrolidone polymer and a polyethylene glycol polymer;
from about 0.1 to about 10%, by weight, of an inorganic salt of peroxymonosulfate, the inorganic salt of peroxymonosulfate being dispersed in the hydratable adhesive film;
water; and
a buffering agent,
wherein all weight percentages are based on the total weight of the strip.

### Claim 2 (depends on 1)

The strip of claim 1, wherein the inorganic salt of peroxymonosulfate is sodium peroxymonosulfate, potassium peroxymonosulfate, or ammonium peroxymonosulfate.

### Claim 3 (depends on 1)

The strip of claim 1, wherein the inorganic salt of peroxymonosulfate is potassium peroxymonosulfate.

### Claim 4 (depends on 3)

The strip of claim 3, wherein the potassium peroxymonosulfate is provided as a triple salt of potassium peroxymonosulfate, potassium hydrogen sulfate and potassium sulfate.

### Claim 5 (depends on 4)

The strip of claim 4, wherein the strip comprises an effective amount of peroxymonosulfate salt which is 0.1 to 5%, by weight of the composition.

### Claim 6 (depends on 1)

The strip of claim 1, wherein the strip does not comprise hydrogen peroxide.

### Claim 7 (depends on 1)

The strip of claim 1, wherein the inorganic salt of peroxymonosulfate is the only oxidizing agent present in the strip.

### Claim 8 (depends on 1)

The strip of claim 1, wherein the hydratable adhesive film comprises about 70 to about 90%, by weight, of the one or more polymers.

### Claim 9 (depends on 1)

A method for whitening teeth comprising the steps of (a) wetting the strip according to claim 1, with water or saliva or assisting, (b) removing any protective backing from the strip, and (c) affixing the adhesive surface of the strip to the teeth for a sufficient period of time to effect whitening of the teeth contacted by the wetted film.

### Claim 10 (depends on 1)

The strip of claim 1, wherein the triple salt of potassium peroxymonosulfate comprises about 45 about 50%, by weight, of the amount of potassium peroxymonosulfate.

### Claim 11

A tooth whitening strip consisting of:
a hydratable adhesive film consisting of:
one or more polyvinylpyrrolidone polymer,
a polyethylene glycol,
an inorganic salt of peroxymonosulfate dispersed in the hydrated adhesive film,
a buffering agent, and
water;
an inert paper or plastic backing affixed to the hydratable adhesive film; and
a removable inert paper or plastic backing removably affixed to the hydratable adhesive film.