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US 12,213,983 B2Granted
Treatment of cancers using PI3 kinase isoform modulators
AssigneeInfinity Pharmaceuticals, Inc.
InventorsHoward M. Stern, Jeffrey L. Kutok
Life of this patent
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Abstract
Provided herein are methods, kits, and pharmaceutical compositions that include a PI3 kinase inhibitor for treating cancers or hematologic disorders.
Claims19
A method of treating a hematologic malignancy in a human subject in need thereof, comprising orally administering to the subject twice daily about 25 mg to about 75 mg of a compound having the following structure or a pharmaceutically acceptable salt, solvate, hydrate, co-crystal, clathrate, or polymorph thereof:
- wherein the hematologic malignancy is chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), CLL/SLL, indolent non-Hodgkin lymphoma (iNHL), peripheral T-cell lymphoma (PTCL), cutaneous T-cell lymphoma (CTCL), or follicular lymphoma (FL).
Dependencies are inferred from the claim text.