# US 12,213,845 B2 · Ultrasound guided femoral artery access system (UFAAS) and method to enhance brain perfusion during neuroprotective CPR

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- Number: US 12,213,845 B2
- Document ID: US12213845B2
- Status: Granted
- Kind: B2
- Application number: 18/501,913
- Filed: 2023-11-03
- Published: 2024-05-09
- Granted: 2025-02-04
- Earliest claimed: 2022-11-03
- Assignees: Resuscitation Innovations LLC
- Applicants: VitalinC LLC
- Inventors: Keith G. Lurie
- Web page: https://patentgrep.com/patent/US12213845B2

## CPC

- A61B 17/3403: {Needle locating or guiding means}
- A61B 90/37: {Surgical systems with images on a monitor during operation}
- A61H 31/007: {Manual driven}
- A61B 2090/372: {Details of monitor hardware}
- A61B 2090/378: {using ultrasound}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61H: PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY (electrotherapy, magnetotherapy, radiation therapy or ultrasound therapy A61N)

## Abstract

A handheld ultrasound guiding system for the transcutaneous delivery of a needle into blood vessel that can be used to then deliver a guidewire, the battery powered light-weight device consisting of a phased array ultrasound generator, a transducer probe, a screen, computer processor that is mechanically coupled to a needle holder mounted at an angle to the ultrasound probe, the needle is mounted such that it can be advanced into a target blood vessel that is being visualized real-time by the ultrasound probe.

## Claims

### Claim 1

A method of performing cardiovascular resuscitation, comprising:
elevating an individual's head, shoulders, and heart relative to the individual's lower body while the individual's lower body remains generally aligned with a horizontal plane;
compressing the individual's chest while the individual's head, shoulders, and heart are elevated;
regulating an intrathoracic pressure of the individual while the individual's head, shoulders, and heart are elevated relative to the lower body; and
performing REBOA on the individual by positioning an intra-aortic balloon in the individual's aorta using an ultrasound-guided cannulation device and inflating the intra-aortic balloon.

### Claim 2 (depends on 1)

The method of performing cardiovascular resuscitation of claim 1, further comprising:
performing active compression decompression cardiopulmonary resuscitation on the individual while the individual is in a supine position in general alignment with the horizontal plane prior to elevating the individual's head, shoulders, and heart.

### Claim 3 (depends on 1)

The method of performing cardiovascular resuscitation of claim 1, further comprising:
actively decompressing the individual's chest between each chest compression.

### Claim 4 (depends on 1)

The method of performing cardiovascular resuscitation of claim 1, wherein:
regulating the intrathoracic pressure comprises interfacing an impedance threshold device with the individual's airway.

### Claim 5 (depends on 1)

The method of performing cardiovascular resuscitation of claim 1, wherein:
elevating the individual's head, shoulders, and heart comprises elevating the individuals' head to a height of between 10 cm and 30 cm above the horizontal plane and elevating the individual's heart to a height of between 5 cm to 15 cm above the horizontal plane.

### Claim 6 (depends on 1)

The method of performing cardiovascular resuscitation of claim 1, wherein:
REBOA is performed on the individual while the individual's head, shoulders, and heart are elevated.

### Claim 7 (depends on 1)

The method of performing cardiovascular resuscitation of claim 1, wherein:
positioning the intra-aortic balloon in the individual's aorta using the ultrasound-guided cannulation device comprises:
locating a femoral artery of the individual using a display device of the ultrasound-guided cannulation device;
inserting a needle into the femoral artery;
advancing a guidewire into the femoral artery via a hollow bore of the needle; and
advancing the intra-aortic balloon to the aorta using the guidewire.

### Claim 8 (depends on 1)

The method of performing cardiovascular resuscitation of claim 1, further comprising:
keeping the intra-aortic balloon in an inflated state for a predetermined period of time after a return of circulation to the individual.

### Claim 9 (depends on 8)

The method of performing cardiovascular resuscitation of claim 8, wherein:
the predetermined period of time is up to one hour.

### Claim 10 (depends on 1)

The method of performing cardiovascular resuscitation of claim 1, further comprising:
deflating the intra-aortic balloon after a return of circulation to the individual upon determining that a physiological measurement of the individual has reached a particular value.

### Claim 11 (depends on 10)

The method of performing cardiovascular resuscitation of claim 10, wherein:
the physiological measurement comprises a blood pressure of the individual.

### Claim 12 (depends on 1)

The method of performing cardiovascular resuscitation of claim 1, further comprising:
deflating the intra-aortic balloon after a return of circulation to the individual, wherein one or both of a timing and a rate of deflation is controlled using a closed loop feedback system with one or more physiologic measurements.

### Claim 13 (depends on 1)

The method of performing cardiovascular resuscitation of claim 1, further comprising:
deflating the intra-aortic balloon after a return of circulation to the individual, wherein one or both of a timing and a rate of deflation is controlled using an open loop feedback system with one or more physiologic measurements.

### Claim 14 (depends on 1)

The method of performing cardiovascular resuscitation of claim 1, further comprising:
deflating the intra-aortic balloon after a return of circulation to the individual, wherein deflation of the intra-aortic balloon is coordinated with a change in elevation of the individual's head, shoulders, and heart.

### Claim 15 (depends on 14)

The method of performing cardiovascular resuscitation of claim 14, wherein:
coordination of the deflation of the intra-aortic balloon is performed by monitoring blood flow to the individual's brain.

### Claim 16 (depends on 15)

The method of performing cardiovascular resuscitation of claim 15, wherein:
monitoring blood flow to the individual's brain is performed using one or both of a measurement of end tidal CO2 and a measurement of cerebral oximetry.
