# US 12,213,809 B2 · In-vivo implantable medical device > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,213,809 B2 - Document ID: US12213809B2 - Status: Granted - Kind: B2 - Application number: 17/162,610 - Filed: 2021-01-29 - Published: 2021-05-20 - Granted: 2025-02-04 - Earliest claimed: 2018-09-27 - Assignees: Murata Manufacturing Co., Ltd. - Applicants: Murata Manufacturing Co., Ltd. - Inventors: Norikazu Sakamoto; Tatsuya Hosotani; Kiyokazu Yamada - Web page: https://patentgrep.com/patent/US12213809B2 ## CPC - A61B 5/686: {Permanently implanted devices, e.g. pacemakers, other stimulators, biochips (A61B5/6861 takes precedence)} - A61B 5/0026: {characterised by the transmission medium} - A61B 5/0031: {Implanted circuitry} - A61L 31/022: {Metals or alloys} - A61L 31/026: {Ceramic or ceramic-like structures, e.g. glasses} - A61L 31/028: {Other inorganic materials not covered by A61L31/022 - A61L31/026} - A61L 31/082: {Inorganic materials} - H01F 27/28: Coils; Windings; Conductive connections - H01F 38/14: Inductive couplings - H02J 7/02: for charging batteries from AC mains by converters - H02J 7/42: with electronic devices having internal batteries, e.g. mobile phones - H02J 50/005: {Mechanical details of housing or structure aiming to accommodate the power transfer means, e.g. mechanical integration of coils, antennas or transducers into emitting or receiving devices} - H02J 50/10: using inductive coupling - H02J 50/12: of the resonant type - H02J 50/80: involving the exchange of data, concerning supply or distribution of electric power, between transmitting devices and receiving devices - H04B 5/26: using coils - H04B 5/43: Antennas - H04B 5/79: for data transfer in combination with power transfer - A61B 5/0036: {including treatment, e.g., using an implantable medical device, ablating, ventilating} - A61B 2560/02: Operational features - A61B 2560/0219: of externally powered implanted units - A61B 2560/0406: specially shaped apparatus housings - A61B 2562/16: Details of sensor housings or probes; Details of structural supports for sensors (A61B2560/0462 takes precedence) - A61L 31/024: {Carbon; Graphite} - A61L 2400/18: Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment - A61N 1/0472: {Structure-related aspects} - A61N 1/05: for implantation or insertion into the body, e.g. heart electrode (A61N1/06 takes precedence) - A61N 1/0529: {Electrodes for brain stimulation} - A61N 1/056: {Transvascular endocardial electrode systems} - A61N 1/08: Arrangements or circuits for monitoring, protecting, controlling or indicating {(for external stimulators A61N1/3603; for implantable neurostimulators A61N1/36128; for heart stimulators A61N1/37; for defibrillators A61N1/3925)} - A61N 1/3605: {Implantable neurostimulators for stimulating central or peripheral nerve system} - A61N 1/36062: {Spinal stimulation} - A61N 1/3787: {from an external energy source} - H01F 27/24: Magnetic cores - H02J 50/70: involving the reduction of electric, magnetic or electromagnetic leakage fields - H02J 2105/46: Medical devices, medical implants or life supporting devices - H04B 5/20: characterised by the transmission technique; characterised by the transmission medium - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) - H01F: MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES - H02J: ELECTRIC POWER NETWORKS; CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY - H04B: TRANSMISSION - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) ## Abstract An in-vivo implantable medical device includes a housing, an electronic circuit component, a power reception coil, and a magnetic material. The housing is formed of a biocompatible material and forms an internal space. The electronic circuit component is disposed in the internal space. The power reception coil is disposed in the internal space, interacts with an external electromagnetic field to form an electromagnetic resonance field to receive power. At least part of a region of the housing in which the electromagnetic resonance field is formed is formed of a biocompatible nonmetal material. ## Claims ### Claim 1 An in-vivo implantable medical device, comprising: a housing including a biocompatible material, and configured to define an internal space sealed; a power reception coil disposed in the internal space and configured to interact with an electromagnetic field generated by an electric field or magnetic field at an outside and generate an electromagnetic resonance field to receive power; a power storage device disposed in the internal space and configured to store power received through the power reception coil; a circuit board disposed in the internal space and including a first main surface and a second main surface opposite the first main surface; an electronic circuit disposed in the internal space and configured to perform at least signal processing by using power received by the power reception coil or power stored in the power storage device, the electronic circuit including an electronic component mounted on the first main surface; and a magnetic material directly attached to the second main surface of the circuit board, wherein the circuit board extends along an entirety of the magnetic material, wherein at least part of a region of the housing in which the electromagnetic resonance field is generated includes a biocompatible nonmetal material, and the power reception coil is a planar coil directly attached to the magnetic material on the second main surface of the circuit board. ### Claim 2 (depends on 1) The in-vivo implantable medical device according to claim 1, wherein the magnetic material is disposed between the power reception coil and the circuit board. ### Claim 3 (depends on 2) The in-vivo implantable medical device according to claim 2, wherein the magnetic material is a planar magnetic sheet and overlaps the power reception coil in plan view of the circuit board. ### Claim 4 (depends on 2) The in-vivo implantable medical device according to claim 2, wherein in plan view of the circuit board, a region where the electronic component is disposed overlaps at least part of a region where the power reception coil is disposed. ### Claim 5 (depends on 1) The in-vivo implantable medical device according to claim 1, wherein a part of the housing other than the region in which the electromagnetic resonance field is generated is made of a biocompatible metal material. ### Claim 6 (depends on 5) The in-vivo implantable medical device according to claim 5, wherein the biocompatible metal material of the housing is a first member having a box-like shape and having an opening, the biocompatible nonmetal material of the housing is a second member having a shape that closes the opening, and a packing having an annular shape and disposed between the first member and the second member is provided. ### Claim 7 (depends on 6) The in-vivo implantable medical device according to claim 6, wherein the housing includes a fixing member in an annular shape including a biocompatible metal material that holds the second member in a direction in which the second member is fitted into the opening of the first member. ### Claim 8 (depends on 7) The in-vivo implantable medical device according to claim 7, wherein the first member and the fixing member respectively have grooves for screw-fitting at contact portions where the first member and the fixing member being in contact with each other. ### Claim 9 (depends on 6) The in-vivo implantable medical device according to claim 6, wherein the packing is made of a biocompatible nonmetal material. ### Claim 10 (depends on 6) The in-vivo implantable medical device according to claim 6, wherein the packing is made of a synthetic polymer compound having a main skeleton by a siloxane bond. ### Claim 11 (depends on 6) The in-vivo implantable medical device according to claim 6, wherein a cross-section in a radial direction from a center of the annular shape of the packing is a substantially L-shape. ### Claim 12 (depends on 6) The in-vivo implantable medical device according to claim 6, wherein a biocompatible oil is applied to the packing. ### Claim 13 (depends on 6) The in-vivo implantable medical device according to claim 6, wherein the biocompatible metal material is a material containing Ti or a titanium alloy made of Ti-6A1-4V as a main component. ### Claim 14 (depends on 13) The in-vivo implantable medical device according to claim 13, wherein the biocompatible metal material is a sintered material of a mixture of ceramic powder and powder of the titanium alloy. ### Claim 15 (depends on 6) The in-vivo implantable medical device according to claim 6, wherein the biocompatible nonmetal material is sapphire, ruby, glass, or ceramic. ### Claim 16 (depends on 6) The in-vivo implantable medical device according to claim 6, wherein the coil generates the electromagnetic resonance field between the coil and a power transmission coil outside the housing and receives power from the power transmission coil. ### Claim 17 (depends on 6) The in-vivo implantable medical device according to claim 6, wherein the magnetic material is configured to define, on a surface side in the housing opposite to the outside, part of a magnetic path of magnetic flux interlinked with the coil. ### Claim 18 (depends on 1) The in-vivo implantable medical device according to claim 1, further comprising: a built-in communication module disposed in the internal space, electrically connected to the electronic circuit, and configured to communicate with an external communication module; and a communication antenna connected to the built-in communication module, wherein at least part of a portion of the housing, that serves as a radiation region of a radio wave of the communication antenna includes a biocompatible nonmetal material. ### Claim 19 (depends on 18) The in-vivo implantable medical device according to claim 18, wherein the biocompatible nonmetal material disposed in the region in which the electromagnetic resonance field is generated and the biocompatible nonmetal material disposed in the portion that serves as the radiation region of the radio wave of the communication antenna are separated from each other. ### Claim 20 (depends on 1) The in-vivo implantable medical device according to claim 1, wherein the electronic circuit includes a wireless communication circuit, and the wireless communication circuit is configured to perform communication using the power reception coil. ### Claim 21 (depends on 1) The in-vivo implantable medical device according to claim 1, further comprising: a feedthrough in part of the housing, wherein the electronic circuit is electrically connected to a biological sensor located outside the housing through the feedthrough. ### Claim 22 (depends on 1) The in-vivo implantable medical device according to claim 1, wherein the circuit board extends along an entirety of the power reception coil. ### Claim 23 An in-vivo implantable medical device, comprising: a housing including a biocompatible material, and configured to define an internal space sealed; a power reception coil disposed in the internal space; a circuit board disposed in the internal space and including a first main surface and a second main surface opposite the first main surface; an electronic circuit disposed in the internal space and configured to perform signal processing with power received by the power reception coil, the electronic circuit including an electronic component mounted on the first main surface; and a magnetic material directly attached to the second main surface of the circuit board, wherein the circuit board extends along an entirety of the magnetic material, wherein a region of the housing, in which the power reception coil faces an outside of the housing, includes a biocompatible nonmetal material, and the power reception coil is a planar coil directly attached to the magnetic material on the second main surface of the circuit board. ### Claim 24 (depends on 23) The in-vivo implantable medical device according to claim 23, wherein a region of the housing other than the region that includes the biocompatible nonmetal material includes a biocompatible metal material. ### Claim 25 (depends on 23) The in-vivo implantable medical device according to claim 23, wherein the magnetic material is configured to constitute part of a magnetic path of magnetic flux interlinked with the power reception coil. ### Claim 26 (depends on 25) The in-vivo implantable medical device according to claim 25, wherein the magnetic material is a magnetic sheet that has a planar shape, the power reception coil is located at a position sandwiched between the magnetic material and the biocompatible nonmetal material, and in plan view of the magnetic material, the magnetic sheet overlaps the power reception coil. ### Claim 27 (depends on 26) The in-vivo implantable medical device according to claim 26, wherein the magnetic material is disposed between the power reception coil and the circuit board. ### Claim 28 (depends on 23) The in-vivo implantable medical device according to claim 23, further comprising: a power storage device configured to store power received by the power reception coil, wherein the power storage device is disposed at one end of the housing in a first direction, and the power reception coil is disposed at another end of the housing in the first direction. ### Claim 29 An in-vivo implantable medical device, comprising: a housing including a biocompatible material and configured to define an internal space sealed; a power reception coil disposed in the internal space; a circuit board disposed in the internal space and including a first main surface and a second main surface opposite the first main surface; an electronic circuit disposed in the internal space and configured to perform signal processing with power received by the power reception coil, the electronic circuit including an electronic component mounted on the first main surface; and a magnetic material directly attached to the second main surface of the circuit board, wherein the circuit board extends along an entirety of the magnetic material, wherein the housing includes a portion made of a biocompatible nonmetal material in a power reception path of power by the power reception coil, a region of the housing other than a region including the biocompatible nonmetal material includes a biocompatible metal material, and the power reception coil is a planar coil directly attached to the magnetic material on the second main surface of the circuit board.