# US 12,213,728 B2 · Temperature controlled short duration ablation with resistive heating

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- Number: US 12,213,728 B2
- Document ID: US12213728B2
- Status: Granted
- Kind: B2
- Application number: 16/856,458
- Filed: 2020-04-23
- Published: 2020-11-05
- Granted: 2025-02-04
- Earliest claimed: 2019-05-01
- Assignees: Biosense Webster (Israel) Ltd.
- Applicants: Biosense Webster (Israel) Ltd.
- Inventors: Keshava Datta; Kristine Fuimaono; Assaf Govari; Andres Claudio Altmann; Tushar Sharma
- Web page: https://patentgrep.com/patent/US12213728B2

## CPC

- A61B 18/1492: {having a flexible, catheter-like structure, e.g. for heart ablation (A61B18/1477 takes precedence)}
- A61B 18/1206: {Generators therefor}
- A61B 34/20: Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
- A61B 2017/00154: {pulsed}
- A61B 2018/00357: {Endocardium}
- A61B 2018/00577: {Ablation}
- A61B 2018/00678: {upper}
- A61B 2018/00702: {Power or energy}
- A61B 2018/00708: {switching the power on or off}
- A61B 2018/00738: {Depth, e.g. depth of ablation}
- A61B 2018/00761: {Duration}
- A61B 2018/00791: {Temperature}
- A61B 2018/00797: {measured by multiple temperature sensors}
- A61B 2018/00875: {Resistance or impedance}
- A61B 2034/2051: {Electromagnetic tracking systems}
- A61B 2090/065: {for measuring contact or contact pressure}
- A61B 2218/002: Irrigation
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

A method, including performing an ablation of tissue using a first high RF power for a short duration, suspending RF power for a predetermined period, and using a second high RF power for a short duration forming lesions with greater surface area and greater depth through resistive heating and thermal latency. High RF power may range between 75-95 W and short duration may range between 4-5 seconds.

## Claims

### Claim 1

A method of ablation comprising:
inserting a catheter into a subject, the catheter having an ablation electrode configured for tissue contact;
performing an ablation session on the tissue for a predetermined total duration of time less than about 18 seconds, including:
applying resistive heating to the tissue by radiofrequency (RF) power via the electrode within a range of about 75 W-95 W for a first duration of about 4 seconds to form a lesion with a depth of about 3.5 mm;
suspending application of RF power to the electrode for a second duration no greater than 10 seconds, during which a temperature of the lesion continues to increase, to allow tissue surrounding the lesion to heat by conduction from the lesion;
measuring temperature of the tissue at least every 33 ms at a depth of about 3 mm to determine dissipation of about 90% of heat of the tissue within about 4 seconds; and
while the tissue surrounding the lesion remains heated by conduction from the lesion, reapplying resistive heating by RF power via the electrode within the range of about 75 W-95 W for a third duration of about 4 seconds to the lesion to increase depth of the lesion to about 4.5 mm into the surrounding tissue.

### Claim 2 (depends on 1)

The method of claim 1, wherein the total duration is less than about 13 seconds.

### Claim 3 (depends on 1)

The method of claim 1, wherein the RF power in the first duration and in the third duration is about 90 W.

### Claim 4 (depends on 1)

The method of claim 1, wherein a rate of temperature increase of the tissue in the first duration is greater than the rate of temperature decrease of the tissue in the second duration.

### Claim 5 (depends on 1)

The method of claim 1, wherein the rate of temperature increase of the tissue in the first duration is generally linear.

### Claim 6 (depends on 1)

The method of claim 1, further including measuring impedance of the tissue every 500 ms.