# US 12,213,719 B2 · Cryoadhesion apparatus

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- Number: US 12,213,719 B2
- Document ID: US12213719B2
- Status: Granted
- Kind: B2
- Application number: 17/626,241
- Filed: 2020-09-29
- Published: 2023-01-05
- Granted: 2025-02-04
- Earliest claimed: 2020-03-23
- Assignees: Accu Target Medipharma (Shanghai) Co., Ltd.
- Applicants: Accu Target Medipharma (Shanghai) Co., Ltd.
- Inventors: Chi Yang; Zhaohua Chang
- Web page: https://patentgrep.com/patent/US12213719B2

## CPC

- A61B 18/02: by cooling, e.g. cryogenic techniques
- A61B 18/0218: {with open-end cryogenic probe, e.g. for spraying fluid directly on tissue or via a tissue-contacting porous tip}
- A61B 1/00133: {Drive units for endoscopic tools inserted through or with the endoscope}
- A61B 2017/00017: {Electrical control of surgical instruments}
- A61B 2017/00469: {for insertion of instruments, e.g. guide wire, optical fibre}
- A61B 2018/00017: {with gas}
- A61B 2018/00023: {closed, i.e. without wound contact by the fluid}
- A61B 2018/00619: {Welding}
- A61B 2018/0063: {Sealing}
- A61B 2018/00744: {Fluid flow}
- A61B 2018/0091: {Handpieces of the surgical instrument or device}
- A61B 2018/00928: {by sending a signal to an external energy source}
- A61B 2018/0094: {Types of switches or controllers}
- A61B 2018/00982: {combined with or comprising means for visual or photographic inspections inside the body, e.g. endoscopes}
- A61B 2018/0212: {using an instrument inserted into a body lumen, e.g. catheter}
- A61B 2018/0262: {using a circulating cryogenic fluid}
- A61B 2018/0293: {using an instrument interstitially inserted into the body, e.g. needle}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

A cryoadhesion apparatus includes a remote control assembly, a valve assembly, a needle catheter assembly, and a gas cylinder, the remote control assembly includes a sheath structure and a remote control, the sheath structure is provided with a catheter channel for the needle catheter assembly to pass through, two ends of the valve assembly are respectively connected to the needle catheter assembly and the gas bottle; the sheath structure is capable of squeezing the needle catheter assembly, when squeezing is maintained, the needle catheter assembly is capable of moving along with the sheath structure under a frictional force between an inner wall of the catheter channel and the needle catheter assembly; the remote control is configured to, when triggered, send a trigger signal to the valve assembly; the valve assembly is configured to transport, when receiving the trigger signal, a gas from the gas cylinder to the needle catheter assembly.

## Claims

### Claim 1

A cryoadhesion apparatus, comprising: a remote control assembly, a valve assembly, a needle catheter assembly, and a gas cylinder, wherein the remote control assembly comprises a sheath structure and a remote control mounted in the sheath structure, the sheath structure is provided with a catheter channel for the needle catheter assembly to pass through, and two ends of the valve assembly are respectively connected to the needle catheter assembly and the gas cylinder;
the sheath structure is capable of squeezing the needle catheter assembly, wherein when squeezing is maintained, the needle catheter assembly is capable of moving along with the sheath structure under a frictional force between an inner wall of the catheter channel and the needle catheter assembly; when the sheath structure does not squeeze the needle catheter assembly, the remote control assembly is capable of moving along the needle catheter assembly;
the remote control is configured to, when triggered, send a trigger signal to the valve assembly;
the valve assembly is configured to transport, when receiving the trigger signal, a gas from the gas cylinder to the needle catheter assembly, to enable the needle catheter assembly to perform freezing;
the sheath structure comprises a remote control sleeve portion, which is provided with a trigger part and a remote control chamber configured to accommodate the remote control; and
the trigger part is capable of triggering, when touched, a button switch of the remote control in the remote control chamber to enable the remote control to transmit the trigger signal when the button switch is triggered.

### Claim 2 (depends on 1)

The cryoadhesion apparatus according to claim 1, wherein the sheath structure further comprises a channel base body, the catheter channel is disposed in the channel base body, and the channel base body is fixedly connected to the remote control sleeve portion.

### Claim 3 (depends on 2)

The cryoadhesion apparatus according to claim 2, wherein the catheter channel in the channel base body comprises a guide channel and a squeezing channel, an inner diameter of the squeezing channel is greater than the guide channel, and an inner wall of the squeezing channel is provided with a soft and rough surface; and
the inner wall of the squeezing channel is capable of deforming when a corresponding position of the channel base body is pinched and squeezing the needle catheter assembly.

### Claim 4 (depends on 3)

The cryoadhesion apparatus according to claim 3, wherein an inner wall of the guide channel is provided with a rigid and smooth surface.

### Claim 5 (depends on 3)

The cryoadhesion apparatus according to claim 3, wherein the valve assembly comprises an electromagnetic valve and a receiving circuit board, and the electromagnetic valve comprises a pin, a pin tube, a pin reset part, a seat, and a pin driving structure; an intake channel is provided inside the pin, the pin passes through the pin tube, an end of the pin tube is configured to be connected to the needle catheter assembly, another end of the pin tube is connected to a side of the seat, and another side of the seat is connected to the gas cylinder; an end of the pin is connected to the needle catheter assembly;
the pin driving structure is configured to, when the receiving circuit board receives the trigger signal, drive the pin to be in an intake position, at which the pin is capable of being inserted into the gas cylinder, so that the gas in the gas bottle enters the intake channel and is transported through the intake channel to the needle catheter assembly; and
the pin reset part is configured to, when the pin driving structure does not drive the pin, drive the pin to reset from the intake position to a non-intake position, at which the pin is not inserted into the gas bottle.

### Claim 6 (depends on 2)

The cryoadhesion apparatus according to claim 2, wherein the sheath structure further comprises a pressing plate, the catheter channel comprises a guide channel, the pressing plate is in rotary connection with the remote control sleeve portion, a side of the pressing plate and opposite to the remote control sleeve portion is provided with a squeezing groove, and an outer surface of the remote control sleeve portion is provided with a squeezing surface; the needle catheter assembly is capable of passing between the squeezing groove and the squeezing surface and passing through the guide channel, and the squeezing surface and/or an inner wall of the squeezing groove is provided with a soft and rough surface;
the pressing plate is configured to: when being pressed to rotate, squeeze the needle catheter assembly through the squeezing groove and the squeezing surface; or
the pressing plate is configured such that: when the pressing plate is not pressed, the squeezing groove and the squeezing surface squeeze the needle catheter assembly, and when the pressing plate is pressed, the squeezing groove and the squeezing surface no longer squeeze the needle catheter assembly.

### Claim 7 (depends on 6)

The cryoadhesion apparatus according to claim 6, wherein the sheath structure further comprises a pressing plate reset part, the pressing plate reset part is connected between the pressing plate and the remote control sleeve portion and configured to, when the pressing plate is not pressed, drive the pressing plate to rotate to reset, so that the needle catheter assembly is no longer squeezed or is squeezed.

### Claim 8 (depends on 6)

The cryoadhesion apparatus according to claim 6, wherein the valve assembly comprises an electromagnetic valve and a receiving circuit board, and the electromagnetic valve comprises a pin, a pin tube, a pin reset part, a seat, and a pin driving structure; an intake channel is provided inside the pin, the pin passes through the pin tube, an end of the pin tube is configured to be connected to the needle catheter assembly, another end of the pin tube is connected to a side of the seat, and another side of the seat is connected to the gas cylinder; an end of the pin is connected to the needle catheter assembly;
the pin driving structure is configured to, when the receiving circuit board receives the trigger signal, drive the pin to be in an intake position, at which the pin is capable of being inserted into the gas cylinder, so that the gas in the gas bottle enters the intake channel and is transported through the intake channel to the needle catheter assembly; and
the pin reset part is configured to, when the pin driving structure does not drive the pin, drive the pin to reset from the intake position to a non-intake position, at which the pin is not inserted into the gas bottle.

### Claim 9 (depends on 2)

The cryoadhesion apparatus according to claim 2, wherein the valve assembly comprises an electromagnetic valve and a receiving circuit board, and the electromagnetic valve comprises a pin, a pin tube, a pin reset part, a seat, and a pin driving structure; an intake channel is provided inside the pin, the pin passes through the pin tube, an end of the pin tube is configured to be connected to the needle catheter assembly, another end of the pin tube is connected to a side of the seat, and another side of the seat is connected to the gas cylinder; an end of the pin is connected to the needle catheter assembly;
the pin driving structure is configured to, when the receiving circuit board receives the trigger signal, drive the pin to be in an intake position, at which the pin is capable of being inserted into the gas cylinder, so that the gas in the gas bottle enters the intake channel and is transported through the intake channel to the needle catheter assembly; and
the pin reset part is configured to, when the pin driving structure does not drive the pin, drive the pin to reset from the intake position to a non-intake position, at which the pin is not inserted into the gas bottle.

### Claim 10 (depends on 1)

The cryoadhesion apparatus according to claim 1, wherein at least one of the sheath structure, the remote control and the needle catheter assembly is disposable.

### Claim 11 (depends on 1)

The cryoadhesion apparatus according to claim 1, wherein the valve assembly comprises an electromagnetic valve and a receiving circuit board, and the electromagnetic valve comprises a pin, a pin tube, a pin reset part, a seat, and a pin driving structure; an intake channel is provided inside the pin, the pin passes through the pin tube, an end of the pin tube is configured to be connected to the needle catheter assembly, another end of the pin tube is connected to a side of the seat, and another side of the seat is connected to the gas cylinder; an end of the pin is connected to the needle catheter assembly;
the pin driving structure is configured to, when the receiving circuit board receives the trigger signal, drive the pin to be in an intake position, at which the pin is capable of being inserted into the gas cylinder, so that the gas in the gas bottle enters the intake channel and is transported through the intake channel to the needle catheter assembly; and
the pin reset part is configured to, when the pin driving structure does not drive the pin, drive the pin to reset from the intake position to a non-intake position, at which the pin is not inserted into the gas bottle.

### Claim 12 (depends on 11)

The cryoadhesion apparatus according to claim 11, wherein the pin comprises a first pin section, a second pin section, a third pin section, and a fourth pin section that are sequentially connected; the first pin section is inserted into an intake chamber of the needle catheter assembly; the fourth pin section is configured to be inserted into the gas cylinder; and an outer diameter of the third pin section matches an inner diameter of the pin tube, an outer diameter of the second pin section is less than an outer diameter of the third pin section, and the pin reset part is disposed on an outer side of the second pin section.

### Claim 13 (depends on 12)

The cryoadhesion apparatus according to claim 12, wherein a side wall of the fourth pin section is provided with an intake vent, and when the pin is inserted into the gas cylinder, a gas is capable of entering the intake channel from the intake vent.

### Claim 14 (depends on 13)

The cryoadhesion apparatus according to claim 13, wherein an inner side of the pin tube is fixedly provided with a pin limit portion, and the pin reset part is connected to the pin limit portion; and the pin limit portion is capable of blocking an end of the third pin section that is far away from the gas bottle, and the pin reset part is located at the outer side of the second pin section to limit a motion position of the pin when reset.

### Claim 15 (depends on 14)

The cryoadhesion apparatus according to claim 14, wherein the pin limit portion comprises at least two fan-shaped limit portions, which are arranged at an interval along a circumferential direction of the pin to form a pressure relief gap between two adjacent fan-shaped limit portions;
the third pin section is provided with a pressure relief groove running through two ends of the third pin section; and
when the pin is not inserted into the gas cylinder, a gas in the intake channel is capable of sequentially flowing through the intake vent, the pressure relief groove, and the pressure relief gap to be discharged to a compartment between the second pin section and an inner wall of the pin tube.

### Claim 16 (depends on 12)

The cryoadhesion apparatus according to claim 12, wherein the outer side of the second pin section is provided with a pin outer thread, which matches and is connected to a limit nut, and the pin reset part is connected to the limit nut; and
the limit nut is capable of adjusting a position of the limit nut relative to the pin by rotating relative to the pin outer thread to change a compression amount or an expansion amount of the pin reset part.

### Claim 17 (depends on 11)

The cryoadhesion apparatus according to claim 11, wherein the needle catheter assembly comprises a needle, a catheter, and a connector structure that are sequentially connected, an intake tube is provided inside the catheter, the connector structure is connected to the valve assembly and is capable of transporting a gas from the valve assembly to the intake tube through which the gas is transported to the needle, and the catheter passes through the catheter channel.

### Claim 18 (depends on 17)

The cryoadhesion apparatus according to claim 17, wherein the connector structure comprises a connector body, a connecting portion, and a head tube; an intake chamber is provided inside the connector body; the connecting portion and the head tube are respectively disposed at two ends of the connector body; and
the intake chamber is configured for the pin of the valve assembly to be inserted after passing through the connecting portion, the intake tube passes through the head tube to be connected to the intake chamber, and the connecting portion is configured to be butt-jointed with the pin tube in the valve assembly.

### Claim 19 (depends on 18)

The cryoadhesion apparatus according to claim 18, wherein the valve assembly further comprises a valve housing, and the electromagnetic valve and the receiving circuit board are disposed inside the valve housing; the valve housing is provided with a first exhaust vent and a second exhaust vent;
the connecting portion is provided with a pressure relief vent, an end of the pressure relief vent is in communication to a compartment between the pin and an inner wall of the pin tube, and another end of the pressure relief vent is in direct or indirect communication to the first exhaust vent in the valve assembly; and
when the pin is not inserted into the gas cylinder, a gas discharged to the compartment between the pin and the inner wall of the pin tube is capable of sequentially flowing through the pressure relief vent, the first exhaust vent, and an inner cavity of the valve housing to be discharged to the second exhaust vent.

### Claim 20 (depends on 17)

The cryoadhesion apparatus according to claim 17, wherein the valve assembly further comprises a valve housing, and the electromagnetic valve and the receiving circuit board are disposed inside the valve housing; and the valve housing is provided with a first exhaust vent and a second exhaust vent;
the needle catheter assembly further comprises a return pipe and a connector housing, the connector structure is disposed inside the connector housing, the connector housing is provided with a connector exhaust vent, the return pipe is connected between the catheter and the connector structure, disposed around an outer side of the intake tube, and in communication to the compartment between the catheter and the intake tube, and a pipe wall of the return pipe is provided with a return vent; and
a gas returning to the compartment between the catheter and the intake tube is capable of sequentially flowing through the return pipe, the return vent, an inner cavity of the connector housing, the connector exhaust vent, the first exhaust vent, and an inner cavity of the valve housing to be discharged to the second exhaust vent.