# US 12,213,679 B2 · Method of applying hemostatic or tissue healing agent to wet surfaces > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,213,679 B2 - Document ID: US12213679B2 - Status: Granted - Kind: B2 - Application number: 18/145,458 - Filed: 2022-12-22 - Published: 2023-04-27 - Granted: 2025-02-04 - Earliest claimed: 2015-10-07 - Assignees: Boston Scientific Scimed, Inc. - Applicants: Boston Scientific Scimed, Inc. - Inventors: Meghan Elizabeth Soens; Andrew Schaubhut; Caroline Riedel; Sergey Kantsevoy - Web page: https://patentgrep.com/patent/US12213679B2 ## CPC - A61B 17/12181: {formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices} - A61B 17/00234: {for minimally invasive surgery (A61B17/0218, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence)} - A61B 17/00491: {Surgical glue applicators} - A61B 2017/00818: {Treatment of the gastro-intestinal system} - A61B 2017/00884: {enhancing wound closure} - A61B 2017/00893: {pharmaceutically effective} - A61B 2017/00951: {adhesive} - A61B 2017/12004: {for haemostasis, for prevention of bleeding} - A61B 2017/1205: {Introduction devices} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract A device for applying a tissue healing agent includes an insertion member extending longitudinally from a proximal end to a distal end and including a channel extending therethrough, a delivery element including a first surface and a second surface opposing one another, the delivery element movable between a closed configuration, in which the delivery element is compressed to be received within the channel, and an open configuration, in which the delivery element is substantially planar, and a first tissue healing agent formed in a sheet configuration and disposed on the first surface of the delivery element. ## Claims ### Claim 1 A method for applying a tissue healing agent to a target tissue, comprising: inserting an insertion member into a living body to the target tissue to be treated, the insertion member extending longitudinally from a proximal end to a distal end and including a channel extending therethrough, a delivery element housed in the insertion member in a closed configuration in which the delivery element is compressed; placing the delivery element distally relative to the insertion member to an open configuration in which the delivery element expands to be substantially planar, the delivery element including first and second opposing surfaces, the first surface including the tissue healing agent formed in a sheet configuration and disposed thereon via a release mechanism from the first surface including an element slidable along the first surface between the first surface and the tissue healing agent to release the tissue healing agent from the first surface; and applying the tissue healing agent against the target tissue to be treated. ### Claim 2 (depends on 1) The method of claim 1, wherein the release mechanism includes an element extendable away from the first surface to release the tissue healing agent therefrom. ### Claim 3 (depends on 1) The method of claim 1, further comprising: removing the delivery element from the target tissue by drawing the delivery element proximally relative to the insertion member until a curved proximal end of the delivery element contacts the distal end of the insertion member, which urges the delivery element toward the closed configuration. ### Claim 4 (depends on 1) The method of claim 1, wherein placing the delivery element in the open configuration includes rotating a control member connected to the delivery element about a longitudinal axis of the control member in a first direction to unroll the delivery element therefrom. ### Claim 5 (depends on 4) The method of claim 4, further comprising: removing the delivery element from the target tissue by rotating the control member about the longitudinal axis in a second direction opposite the first direction to roll the delivery element thereabout toward the closed configuration. ### Claim 6 (depends on 1) The method of claim 1, wherein the delivery element is biased toward the open configuration and is constrained in the closed configuration via an interior surface of the channel. ### Claim 7 (depends on 1) The method of claim 1, wherein, in the closed configuration, the delivery element is rolled upon itself to be received within the channel. ### Claim 8 (depends on 1) The method of claim 1, wherein the tissue healing agent has adhesive properties. ### Claim 9 (depends on 1) The method of claim 1, wherein the tissue healing agent includes at least one of a steroid, a polymer, a polyglycolic acid, a fibrin glue and a tissue cell matrix sheet. ### Claim 10 A method for applying tissue healing agents to a target tissue, comprising: inserting an insertion member into a living body to the target tissue to be treated, the insertion member extending longitudinally from a proximal end to a distal end and including a channel extending therethrough, a delivery element housed in the insertion member in a closed configuration in which the delivery element is compressed; placing the delivery element distally relative to the insertion member to an open configuration in which the delivery element expands to be substantially planar, the delivery element including a first surface and a second surface opposite the first surface, the first surface including a first tissue healing agent formed in a sheet configuration and disposed thereon by releasing the first tissue healing agent from the delivery element via a first release mechanism which releases the first tissue healing agent from the first surface, applying a second tissue healing agent against a second portion of the target tissue to be treated, the second tissue healing agent being formed in a sheet configuration and disposed on the second surface of the delivery element; and applying the first tissue healing agent against a first portion of the target tissue to be treated. ### Claim 11 (depends on 10) The method of claim 10, further comprising: releasing the second tissue healing agent from the delivery element via a second release mechanism which releases the second tissue healing agent from the second surface. ### Claim 12 (depends on 11) The method of claim 11, wherein the first release mechanism includes a first element slidable along the first surface between the first surface and the first tissue healing agent to release the first tissue healing agent from the first surface. ### Claim 13 (depends on 12) The method of claim 12, wherein the second release mechanism includes a second element slidable along the second surface between the second surface and the second tissue healing agent to release the second tissue healing agent from the second surface. ### Claim 14 (depends on 10) The method of claim 10, wherein the first release mechanism includes an element extendable away from the first surface to release the first tissue healing agent therefrom. ### Claim 15 (depends on 10) The method of claim 10, further comprising: removing the delivery element from the target tissue by drawing the delivery element proximally relative to the insertion member until a curved proximal end of the delivery element contacts the distal end of the insertion member, which urges the delivery element toward the closed configuration.