# US 12,213,665 B2 · Methods for closing a wound > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,213,665 B2 - Document ID: US12213665B2 - Status: Granted - Kind: B2 - Application number: 17/558,691 - Filed: 2021-12-22 - Published: 2022-08-04 - Granted: 2025-02-04 - Earliest claimed: 2021-02-04 - Assignees: Olympus Medical Systems Corp. - Applicants: Olympus Medical Systems Corp. - Inventors: Keita Ozawa; Kunihide Kaji - Web page: https://patentgrep.com/patent/US12213665B2 ## CPC - A61B 17/06166: {Sutures (suture materials A61L17/00; manufacture of artificial threads D01D; treatment of threads D06M)} - A61B 17/0466: {Suture bridges} - A61B 17/0469: {Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery} - A61B 2017/00269: {endoscopic mucosal resection EMR} - A61B 2017/00818: {Treatment of the gastro-intestinal system} - A61B 2017/06176: {with protrusions, e.g. barbs} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract A method for closing a wound in a mucosal layer of an organ wall of a patient includes threading a suture thread into the mucosal layer at a first position located on a first side of the wound, threading the suture thread at least once into a muscle layer of the organ wall, and threading the suture thread into the mucosal layer at a second position located on a second side of the wound that is opposite the first side of the wound. A method for resecting a lesion in a wall of an organ of a patient includes creating a wound in a mucosal layer of the wall of the organ by excising the lesion from the wall of the organ, and threading a suture thread through a series passes between the mucosal layer on a first side of the wound and the mucosal layer on a second side of the wound, the suture thread being threaded into a muscle layer of the wall of the organ in at least one pass of the series passes. ## Claims ### Claim 1 A method for closing a wound in a mucosal layer of a luminal organ wall of a patient, the method comprising: passing a suture thread through the mucosal layer at a first position located on a first side of the wound, the suture thread exiting the mucosal layer at a second position proximate an edge of the wound on the first side of the wound; inserting the suture thread into an exposed surface of a muscle layer to a third position within the muscle layer and turning the suture thread within the muscle layer such that the suture thread exits out of the exposed surface of the muscle layer, wherein the exposed surface of the muscle layer is exposed toward an interior of the luminal organ by resecting a section of the mucosal layer from the muscle layer; and passing the suture thread through the mucosal layer at a fourth position located on a second side of the wound that is opposite the first side of the wound, wherein a portion of the suture thread between the first position and the fourth position is within the muscle layer. ### Claim 2 (depends on 1) The method of claim 1, wherein the third position within the muscle layer is centrally located between the first side and the second side of the wound. ### Claim 3 (depends on 1) The method of claim 1, wherein the suture thread comprises a plurality of barbs configured to anchor the suture thread in the muscle layer. ### Claim 4 (depends on 1) The method of claim 1, wherein the wound does not extend through an entire thickness of the luminal organ wall. ### Claim 5 (depends on 1) The method of claim 1, wherein the suture thread does not pass through an entire thickness of the muscle layer. ### Claim 6 (depends on 1) The method of claim 1, further comprising moving the first side of the wound toward the second side of the wound while lifting the muscle layer towards the mucosal layer by pulling the suture thread. ### Claim 7 (depends on 1) The method of claim 1, wherein the exposed surface of the muscle layer extends perpendicular to a thickness of the wall of the luminal organ at the exposed surface. ### Claim 8 (depends on 1) The method of claim 1, further comprising pulling the suture thread to lift the exposed surface of the muscle layer toward the interior of the luminal organ to reduce a space between the mucosal layer and the muscular layer; wherein the mucosal layer on the first side of the wound and the mucosal layer on the second side of the wound are sutured together with the exposed surface of the muscle layer that is lifted toward the interior of the luminal organ. ### Claim 9 (depends on 1) The method of claim 1, further comprising pulling the suture thread to lift the exposed surface of the muscle layer toward the first and second position to reduce a space between the mucosal layer and the muscle layer. ### Claim 10 A method for closing a wound of a luminal organ of a patient, the method comprising: creating a wound in a mucosal layer of a wall of the luminal organ by excising a lesion from the wall of the luminal organ, wherein excising the lesion exposes a surface of a muscle layer of the wall of the luminal organ beneath the lesion, the exposed surface of the muscle layer facing towards an interior of the luminal organ; and passing a suture thread through a series of passes between the mucosal layer on a first side of the wound and the mucosal layer on a second side of the wound, wherein in at least one pass of the series of passes the suture thread is inserted through a position on the exposed surface of the muscle layer to a location within the muscle layer and turned within the muscle layer to exit out of the exposed surface of the muscle layer at another position, wherein a portion of the suture thread between the mucosal layer on a first side of the wound and the mucosal layer on a second side of the wound is within the muscle layer. ### Claim 11 (depends on 10) The method of claim 10, wherein the location within the muscle layer is centrally located between the first side and the second side of the wound. ### Claim 12 (depends on 10) The method of claim 10, wherein the suture thread is inserted into the exposed surface of the muscle layer in only one pass of the series passes. ### Claim 13 (depends on 10) The method of claim 10, wherein the exposed surface of the muscle layer extends perpendicular to a thickness of the wall of the luminal organ at the exposed surface. ### Claim 14 (depends on 10) The method of claim 10, further comprising pulling the suture thread to lift the exposed surface of the muscle layer toward the interior of the luminal organ to reduce a space between the mucosal layer and the muscular layer; wherein the mucosal layer on the first side of the wound and the mucosal layer on the second side of the wound are sutured together with the exposed surface of the muscle layer that is lifted toward the interior of the luminal organ. ### Claim 15 (depends on 10) The method of claim 10, further comprising pulling the suture thread to lift the exposed surface of the muscle layer toward the first and second sides of the wound to reduce a space between the mucosal layer and the muscle layer. ### Claim 16 A method for closing a wound of a luminal organ of a patient, the method comprising: creating an exposed surface of a muscle layer by excising a portion of a mucosal layer of a wall of the luminal organ, the exposed surface of the muscle layer facing towards an interior of the luminal organ; passing a suture thread through the mucosal layer around the exposed surface of the muscle layer; and inserting the suture thread through a position on the exposed surface of the muscle layer to a location within the muscle layer and turning the suture thread within the muscle layer such that the suture thread exits out of the exposed surface of the muscle layer at another position, wherein a portion of the suture thread is within the muscle layer. ### Claim 17 (depends on 16) The method of claim 16, wherein the suture thread is an absorbable suture thread. ### Claim 18 (depends on 16) The method of claim 16, wherein the suture thread does not pass through an entire thickness of the muscle layer. ### Claim 19 (depends on 16) The method of claim 16, wherein the exposed surface of the muscle layer extends perpendicular to a thickness of the wall of the luminal organ at the exposed surface. ### Claim 20 (depends on 16) The method of claim 16, further comprising pulling the suture thread to lift the exposed surface of the muscle layer toward the edge of the wound to reduce a space between the mucosal layer and the muscle layer.