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US 12,213,464 B2Granted
Single nucleotide polymorphisms and feeding efficiency in cattle
AssigneeThe Governors of the University of Alberta
InventorsGraham Plastow, Mohammed Abo-Ismail
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Abstract
Methods of identifying cattle having increased feed efficiency using a small panel of single nucleotide polymorphisms is provided. The method provides for using a thousand or less of such SNPs and includes using a panel of 250 or fewer SNPs. The method if useful with various cattle breeds including crossbred cattle. Provided are SNPs that are useful as markers with various traits associated with feed efficiency in cattle. Kits and methods of use are provided.
Claims23
A method for producing meat from or breeding a Bos taurus animal having increased feed efficiency, the method comprising:
- obtaining nucleic acid samples from members of a population of Bos taurus animals;
- genotyping the samples to detect alleles of single nucleotide polymorphisms (SNPs) in a panel of SNPs for each member of the population, wherein the panel of SNPs comprises rs109382589, rs208660945, rs43702346, rs137601357, rs210072660, rs133057384, rs41821600, rs476872493, rs134264563, rs385640152, rs43020736, rs110216983, rs109930382, rs109558734, and rs209765899;
- assigning a molecular breeding value to each animal in the population, wherein the molecular breeding value is calculated from allele substitution effects on at least one feed efficiency phenotype for each detected allele in the SNP panel for the animal, and wherein the at least one feed efficiency phenotype comprises Residual Feed Intake (RFI) and/or Residual Feed Intake adjusted for backfat (RFIf);
- and
- producing meat from and/or breeding a Bos taurus animal from the population having a molecular breeding value in the top 16% of the population.
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