Methods and systems for controlling blood pressure by controlling atrial pressure

A system for reducing blood pressure comprising:

• at least one stimulation electrode for stimulating at least one chamber of a heart of a patient;
• and
• at least one controller configured to:
• deliver through the at least one stimulation electrode, to the heart of the patient, a first stimulation pattern having first stimulation parameters,
• continuously receive, during delivery of the first stimulation pattern, input data relating to systemic blood pressure of the patient,
• determine a measured systemic blood pressure based on the input data,
• compare the measured systemic blood pressure to a target blood pressure value set for the patient;
• adjust the first stimulation parameters into second stimulation parameters configured to change systemic blood pressure of the patient to be closer to the target blood pressure value by:
• comparing:
• sensed blood pressure parameter values to a target,
• sensed blood pressure parameter values between two or more stimulation patterns,
• calculated values relating to two or more stimulation patterns, and/or
• additional sensed parameters between two or more stimulation patterns,
• determining the second stimulation parameters based on the comparing, and
• adjusting the first stimulation parameters to the determined second stimulation parameters;
• and
• deliver through the at least one electrode, to the heart of the patient, a second stimulation pattern having the second stimulation parameters.

A method for setting a stimulation pattern for reducing blood pressure in a patient, the method comprising:

• setting a target blood pressure value for the patient, wherein the target blood pressure value comprises a reduction of at least 4% from a pretreatment blood pressure of the patient;
• applying to a heart of the patient a first stimulation pattern having first stimulation parameters;
• while applying the first stimulation pattern, continuously measuring systemic blood pressure of the patient;
• comparing the measured systemic blood pressure to the target blood pressure value;
• adjusting the first stimulation parameters into second stimulation parameters configured to change systemic blood pressure of the patient to be closer to the target blood pressure value;
• and
• applying to the heart of the patient a second stimulation pattern having the second stimulation parameters.