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US 12,203,938 B2Granted
Levetiracetam immunoassays
AssigneeARK Diagnostics, Inc.
InventorsJohnny Jose Valdez, Byung Sook Moon, Ki Chung, Alejandro A. Orozco
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Abstract
Methods, compositions and kits are disclosed directed at levetiracetam derivatives, immunogens, signal generating moieties, antibodies that bind levetiracetam and immunoassays for detection of levetiracetam.
Claims8
A method for detecting levetiracetam, the method comprising:
- combining in a reaction mixture (a) a sample suspected of containing levetiracetam, (b) at least one polyclonal anti-levetiracetam antibody and (c) a compound of Formula 1:
- wherein:
- R1 is selected from the group consisting of —(CH2)n—NH—C(O)—(CH2)n—C(O)—Z and —(CH2)n—NH—C(O)—(CH2)n—S—(CH2)n—C(O)—Z, wherein each n is an integer from 1 to 10;
- and
- Z is an enzyme, and
- acid salts thereof;
- and
- measuring the activity of the enzyme, whereby the activity of the enzyme indicates the presence of levetiracetam in the sample.
5 more elements
Dependencies are inferred from the claim text.