N-pyridinyl acetamide derivatives as inhibitors of the Wnt signaling pathway
AssigneeRedx Pharma PLC
InventorsInder Bhamra, Matilda Bingham, Richard Testar, Louise Sargent, Craig Donoghue
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AssigneeRedx Pharma PLC
InventorsInder Bhamra, Matilda Bingham, Richard Testar, Louise Sargent, Craig Donoghue
Estimating the term…
This invention relates to compounds. More specifically, the invention relates to compounds useful as inhibitors of the Wnt signalling pathway. Specifically, inhibitors of Porcupine (Porcn) are contemplated by the invention. In addition the invention contemplates processes to prepare the compounds and uses of the compounds. The compounds of the invention may therefore be used in treating conditions mediated by the Wnt signalling pathway, for example treating cancer, sarcoma, melanoma, skin cancer, haematological tumors, lymphoma, carcinoma, and leukemia; or enhancing the effectiveness of an anti-cancer treatment.
A compound which is:
A compound which is:
A method of treating a condition in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of the compound:
A method of treating a condition in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of the compound:
Dependencies are inferred from the claim text.