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US 12,202,782 B2Granted
Processes and intermediates for preparing MCL1 inhibitors
AssigneeGilead Sciences, Inc.
InventorsDarryl D. Dixon, Michael A. Ischay, Trevor C. Johnson, Jeffrey E. Merit, Christopher S. Regens, Eric A. Standley, Dietrich P. Steinhuebel
Life of this patent
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Abstract
The present disclosure relates to methods and intermediates for the synthesis of certain compounds that inhibit MCL1, for use in the treatment of cancers.
Claims2
A compound selected from:
- wherein
- each Rn is independently C1-6alkyl, or the two Rn moieties join together to form a C2-4alkyl bridge, wherein the bridge is optionally substituted by one to four groups independently selected from C1-3alkyl and phenyl;
- and
- Rz is halogen or CN.
1 more element
Dependencies are inferred from the claim text.