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US 12,201,583 B2Granted
Pharmaceutical dosage system
AssigneeVanda Pharmaceuticals Inc.
InventorsAndrew Mayne, Petra Lutz, Paromita Sarkar, Galina Gouvea
Life of this patent
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Abstract
A pharmaceutical dosage system includes a blister pack and a plurality of dosage forms contained by the blister pack. The dosage forms are to be consumed in an up-titration process. Only one single dosage form of the plurality of dosage forms is consumed on a given day throughout the up-titration process whereby dosages increase over the course of a multi-day period of time.
Claims12
A pharmaceutical dosage system comprising:
- an inner wallet that includes multiday blister pack having a plurality of blisters that at least partially define a corresponding plurality of cavities, and an inner panel that carries the blister pack, wherein the blisters extend through respective openings of the inner panel;
- and
- a plurality of pharmaceutical dosage forms disposed in respective cavities of the plurality of cavities, such that each cavity of the plurality of cavities contains only a single one of the plurality of pharmaceutical dosage forms, wherein the cavities are accessible so as to consume the pharmaceutical dosage forms on respective unique days over a multi-day period, and all active ingredients of each of the pharmaceutical dosage forms are substantially identical to each other,
- wherein the pharmaceutical dosage forms are arranged along the inner wallet sequentially in the order in which they are to be consumed,
- wherein each of the pharmaceutical dosage forms includes indicia that visually distinguish each of the pharmaceutical dosage forms from one or more others of the single pharmaceutical dosage forms,
- wherein the inner wallet contains earmarking information that sets forth a dosing schedule during which of the pharmaceutical dosage forms are to be consumed over the multi day period, and
- wherein the pharmaceutical dosage forms comprise:
- two of a first pharmaceutical dosage form earmarked by the earmarking information to be consumed on respective first and second days of the multi-day period, wherein the first pharmaceutical dosage forms contain approximately 2 mg of active ingredient;
- two of a second pharmaceutical dosage form earmarked by the earmarking information to be consumed on respective third and fourth days of the multi-day period, wherein the second pharmaceutical dosage forms contain approximately 3 mg of active ingredient;
- two of a third pharmaceutical dosage form earmarked by the earmarking information to be consumed on respective fifth and sixth days of the multi-day period, wherein the third pharmaceutical dosage form contains approximately 4 mg of active ingredient;
- a fourth pharmaceutical dosage form earmarked by the earmarking information to be consumed on a seventh day of the multi-day period, wherein the fourth pharmaceutical dosage form contains approximately 5 mg of active ingredient;
- a fifth pharmaceutical dosage form earmarked by the earmarking information to be consumed on an eighth day of the multi-day period, wherein the fifth pharmaceutical dosage form contains approximately 6 mg of active ingredient;
- a sixth pharmaceutical dosage form earmarked by the earmarking information to be consumed on a ninth day of the multi-day period, wherein the sixth pharmaceutical dosage form contains approximately 7 mg of active ingredient;
- a seventh pharmaceutical dosage form earmarked by the earmarking information to be consumed on a tenth day of the multi-day period, wherein the seventh pharmaceutical dosage form contains approximately 8 mg of active ingredient;
- an eighth pharmaceutical dosage form earmarked by the earmarking information to be consumed on an eleventh day of the multi-day period, wherein the eighth pharmaceutical dosage form contains approximately 9 mg of active ingredient;
- and
- three of a ninth pharmaceutical dosage form earmarked by the earmarking information to be consumed on respective twelfth, thirteenth, and fourteenth days of the multi-day period, wherein the ninth pharmaceutical dosage form contains approximately 10 mg of active ingredient.
14 more elements
Dependencies are inferred from the claim text.