Stimulated Raman photothermal microscope
AssigneeTrustees of Boston University
InventorJi-Xin Cheng
Life of this patent
Estimating the term…
Abstract
A stimulated Raman photothermal (SRP) microscope for imaging a sample. A first optical source omits an intensity-modulated pump beam. A second optical source omits an intensity-modulated Stokes beam. The Stokes beam is combined with the pump beam to form a combined beam. The combined beam is directed to the sample to induce a thermal effect caused by the stimulated Raman process. A third optical source emits a probe beam, the probe beam is directed to the sample. An optical detector detects modulation of the probe beam after modulation by the sample to measure an SRP signal.
Claims20
A stimulated Raman photothermal (SRP) microscope for imaging a sample, comprising:
- a first optical source emitting an intensity-modulated pump beam;
- a second optical source emitting an intensity-modulated Stokes beam, wherein the Stokes beam is combined with the pump beam to form a combined beam, the combined beam being directed to the sample to induce a thermal effect caused by the stimulated Raman process;
- a third optical source emitting a probe beam, wherein the probe beam is directed to the sample;
- and an optical detect or configured to detect modulation of the probe beam after modulation by the sample to measure an SRP signal.
A stimulated Raman photothermal (SRP) microscope for imaging a sample, comprising:
- a first optical source emitting an intensity-modulated pump beam;
- a second optical source emitting an intensity-modulated Stokes beam, wherein the Stokes beam is combined with the pump beam to form a combined beam, the combined beam being directed to the sample to induce a thermal effect caused by the stimulated Raman process;
- a fiber laser emitting a probe beam, wherein the probe beam is directed to the sample;
- and a photodiode configured to detect modulation of the probe beam after modulation by the sample to measure an SRP signal.
Dependencies are inferred from the claim text.