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US 12,194,194 B2Granted
Soft tissue protein compositions, methods of making, and uses thereof
AssigneeAdvanced Biologics, Inc.
InventorsAmit Prakash Govil, Bryan Choi, Sahil Jalota
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Abstract
Provided herein are soluble soft tissue protein compositions that can contain one or more soft-tissue bioactive factors, methods of making the soluble soft tissue protein compositions, and methods of using the soluble soft tissue protein compositions.
Claims16
A dehydrated soluble soft tissue protein composition comprising a bioactive factor, where the dehydrated soluble soft tissue protein composition is made by a method comprising:
- harvesting soft tissue from a donor to obtain harvested soft tissue, where the soft tissue contains soft tissue cells;
- heating the harvested soft tissue to at least 20° C.;
- lysing the soft tissue cells by osmotic shock without a detergent to obtain a soft tissue cell lysate;
- isolating the soft tissue lysate from the soft tissue to yield the soluble soft tissue protein composition;
- and
- dehydrating the soluble soft tissue lysate to obtain a dehydrated soluble soft tissue protein composition.
3 more elements
Dependencies are inferred from the claim text.