US 12,194,070 B2 · Traditional chinese medicine compound for improving testicular dysfunction, preparation method and application thereof

Abstract

A traditional Chinese medicine compound for improving testicular dysfunction is made from the following raw materials: Codonopsis pilosula, Astragalus membranaceus, Dioscorea opposita, Angelica sinensis, Atractylodes macrocephala, Poria cocos, Cynanchum otophyllum, Psoralea corylifolia, Ligusticum chuanxiong, Nelumbo nucifera, Euryale ferox, Amomum villosum, Alpinia katsumadai, Foeniculum vulgare, Cinnamomum cassia, Evodia ruticarpa, Piper nigrum, Zingiber officinale, Aconitum carmichaelii, and Glycyrrhiza uralensis. All the raw materials are combined, so that the spleen, the stomach and the kidney are in harmony, the qi, the blood and the body fluid are recovered, and the kidney essence is active. Animal experiments show that the traditional Chinese medicine compound can up-regulate expressions of phosphatidylinositol 3-kinase (PI3K), phospho-protein kinase B (p-AKT) and B-cell lymphoma-2 (Bcl-2), improve testicular dysfunction, improve hormone secretion, regulate a male reproductive endocrine environment of the body, and further improve semen parameters.

Claims6

Dependent claims

A method of improving testicular dysfunction, comprising:

applying a traditional Chinese medicine compound to a subject in need thereof, wherein the traditional Chinese medicine compound is made from the following raw materials in parts by weight:
10-40 parts of Codonopsis pilosula, 15-100 parts of Astragalus membranaceus, 10-40 parts of Dioscorea opposita, 6-25 parts of Angelica sinensis, 6-40 parts of Atractylodes macrocephala, 10-30 parts of Poria cocos, 10-30 parts of Cynanchum otophyllum, 6-15 parts of Psoralea corylifolia, 6-20 parts of Ligusticum chuanxiong, 6-20 parts of Nelumbo nucifera, 6-20 parts of Euryale ferox, 3-10 parts of Amomum villosum, 3-10 parts of Alpinia katsumadai, 6-20 parts of Foeniculum vulgare, 3-15 parts of Cinnamomum cassia, 6-10 parts of Evodia rutaecarpa, 6-15 parts of Piper nigrum, 6-15 parts of Zingiber officinale, 6-15 parts of Aconitum carmichaelii, and 6-10 parts of Glycyrrhiza uralensis.

Dependencies are inferred from the claim text.

Traditional chinese medicine compound for improving testicular dysfunction, preparation method and application thereof

Life of this patent

Traditional chinese medicine compound for improving testicular dysfunction, preparation method and application thereof

Life of this patent

Abstract

Claims6