Signatures and determinants for diagnosing infections and methods of use thereof
AssigneeMeMed Diagnostics Ltd.
InventorsKfir Oved, Eran Eden, Ilan Ifergan
Life of this patent
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Abstract
A kit is disclosed for distinguishing between bacterial and viral infections. One of the antibodies of the kit specifically binds to TNF-related apoptosis-inducing ligand (TRAIL) protein and another of the antibodies of the kit specifically binds to Procalcitonin (PCT) protein.
Claims8
A kit comprising antibodies, at least one of said antibodies is a monoclonal antibody, wherein a first antibody of said antibodies specifically binds to TNF-related apoptosis-inducing ligand (TRAIL) protein, a second antibody of said antibodies specifically binds to Procalcitonin (PCT) protein, and a third antibody of said antibodies specifically binds to C-Reactive protein (CRP), wherein the kit does not comprise more than three additional antibodies which specifically bind to additional determinants, each of said three additional antibodies targeting a different soluble determinant of said additional determinants, wherein said determinant is a protein whose level is differentially expressed in a viral and bacterial infection.
A kit comprising antibodies immobilized on a solid support, wherein said antibodies consist of a first antibody that specifically binds to TRAIL protein, a second antibody that specifically binds to PCT protein and a third antibody that specifically binds to C-Reactive protein (CRP).
Dependencies are inferred from the claim text.