1,2-diacylglycerol compound, preparation method therefor, and immunomodulator containing same as active ingredient
AssigneeEnzychem Lifesciences Corporation
InventorsKi Young Sohn, Jae Wha Kim, Sun Young Yoon, Chang Hyun Yoo, Jin Seon Jeong
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Abstract
Disclosed are a novel 1,2-diacylglycerol compound that useful for improving, preventing or treating inflammation-related diseases by inhibiting overexpression of various inflammatory cytokines such as IL-4 and IL-6 or chemokine CXCL8 related to the migration of inflammatory cells, a method for preparing the same, and an immunomodulator containing the same as an active ingredient. The 1,2-diacylglycerol compound is represented by Chemical Formula 2 in the patent specification.
Claims10
A 1,2-diacylglycerol compound represented by following Chemical formula 2,
- wherein in Chemical formula 2, R1 is octanoyl, lauroyl, decanoyl or palmitoyl, R3 is butyryl, 2-methylbutyryl, pivaloyl or linoleoyl, and R2 is methyl group, ethyl group, propyl group or isopropyl group.
An immunomodulator comprising the 1,2-diacylglycerol compound represented by following Chemical formula 2 as an active ingredient,
- wherein in Chemical formula 2, R1 is octanoyl, lauroyl, decanoyl or palmitoyl, R3 is butyryl, 2-methylbutyryl, pivaloyl or linoleoyl, and R2 is methyl group, ethyl group, propyl group or isopropyl group.
A health functional food composition for immunity enhancement, comprising the 1,2-diacylglycerol compound represented by following Chemical formula 2 as an active ingredient,
- wherein in Chemical formula 2, R1 is octanoyl, lauroyl, decanoyl or palmitoyl, R3 is butyryl, 2-methylbutyryl, pivaloyl or linoleoyl, and R2 is methyl group, ethyl group, propyl group or isopropyl group.
Dependencies are inferred from the claim text.