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US 12,186,709 B2Granted
Three-compartment bipolar membrane electrodialysis of salts of amino acids
AssigneeMonsanto Technology LLC
InventorsEduardo Aurelio Casanova, Justin Robert Struble, Jian Xu
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Abstract
This invention relates to an improved electrodialysis method for preparing an amino acid from a salt of the amino acid utilizing a three-compartment bipolar membrane electrodialysis process wherein an aqueous electrolyte comprising an exogenous acid is added to the acid compartment of a three-compartment bipolar membrane apparatus. The exogenous acid is different than the amino acid and typically has a pKa less than the pKa of the amino acid.
Claims29
A process for preparing an amino acid, the process comprising:
- introducing an aqueous electrolyte comprising a first acid into an acid compartment of a three-compartment electrodialysis bipolar membrane cell comprising an acid compartment, a salt compartment, and a base compartment;
- introducing a feed salt stream comprising a salt of the amino acid into the salt compartment of the three-compartment bipolar membrane cell, wherein the salt of the amino acid is formed by reacting an amino acid with a base;
- and
- introducing an aqueous stream into the base compartment of the three-compartment bipolar membrane cell;
- wherein the first acid and the amino acid are different, and the amino acid has a pKa greater than 2.0 and the first acid introduced into the acid compartment of the three-compartment bipolar membrane cell has a pKa less than the pKa of the amino acid, and wherein:
- the three-compartment bipolar membrane cell further comprises a cathode and an anode, the process further comprising applying an electric potential between the cathode and the anode.
3 more elements
A process for preparing an amino acid, the process comprising:
- introducing a feed salt stream comprising a salt of the amino acid into the salt compartment of a two-compartment electrodialysis bipolar membrane cell comprising a salt compartment and a base compartment;
- introducing the product from the salt compartment of the two-compartment electrodialysis bipolar membrane cell into the salt compartment of a three-compartment electrodialysis bipolar membrane cell comprising an acid compartment, a salt compartment, and a base compartment;
- introducing an aqueous electrolyte comprising a first acid into the acid compartment of the three-compartment electrodialysis bipolar membrane cell;
- and
- introducing an aqueous stream into the base compartment of the three-compartment electrodialysis bipolar membrane cell;
- wherein the first acid and the amino acid are different.
3 more elements
A process for preparing an amino acid, the process comprising:
- introducing a feed salt stream comprising a salt of the amino acid into the salt compartment of a two-compartment electrodialysis bipolar membrane cell comprising a salt compartment, a base compartment, an anode and a cathode, wherein the salt compartment of the two-compartment bipolar membrane is bounded by a bipolar membrane and an cation exchange membrane and the base compartment of the two-compartment of the two-compartment bipolar membrane is bounded the cation exchange membrane bounding the salt compartment and second bipolar membrane;
- applying an electric potential between the cathode and the anode of the two-compartment bipolar membrane cell, thereby inducing flow of cations from the salt of the amino acid in the salt compartment through the cation exchange membrane into the base compartment of the two-compartment bipolar membrane cell;
- recovering a base product from the base compartment of the two-compartment bipolar membrane cell;
- introducing the product from the salt compartment of the two-compartment electrodialysis bipolar membrane cell into the salt compartment of a three-compartment electrodialysis bipolar membrane cell comprising an acid compartment, a salt compartment, a base compartment, an anode and a cathode,
- introducing an aqueous electrolyte comprising a first acid into the acid compartment of the three-compartment electrodialysis bipolar membrane cell;
- and
- introducing an aqueous stream into the base compartment of the three-compartment electrodialysis bipolar membrane cell;
- wherein the product from the salt compartment of the two-compartment bipolar membrane cell comprises an amino acid salt different from the amino acid salt introduced into the salt compartment of the two-compartment bipolar membrane cell.
5 more elements
Dependencies are inferred from the claim text.