# US 12,185,909 B2 · System and method for cleansing segments of a luminal network > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,185,909 B2 - Document ID: US12185909B2 - Status: Granted - Kind: B2 - Application number: 17/029,263 - Filed: 2020-09-23 - Published: 2021-01-07 - Granted: 2025-01-07 - Earliest claimed: 2016-09-19 - Assignees: Covidien LP - Applicants: Covidien LP - Inventors: William S. Krimsky - Web page: https://patentgrep.com/patent/US12185909B2 ## CPC - A61B 1/00082: {Balloons} - A61B 1/00085: {Baskets} - A61B 1/015: Control of fluid supply or evacuation - A61B 1/018: for receiving instruments - A61B 5/062: {using magnetic field} - A61B 10/0045: {Devices for taking samples of body liquids} - A61B 10/02: Instruments for taking cell samples or for biopsy {(A61B10/0038 and A61B10/0045 take precedence; needle locating or guiding means A61B17/3403; samplers for enzymology or microbiology C12M1/26; sampling or preparing biological specimens G01N33/48)} - A61M 13/00: Insufflators for therapeutic or disinfectant purposes {, i.e. devices for blowing a gas, powder or vapour into the body (hand-held units in which gas flow is produced by muscular energy at the moment of use B05B11/062)} - A61M 16/0404: {with means for selective or partial lung respiration} - A61M 16/0459: {one cuff behind another} - A61M 16/0479: {above the cuff, e.g. giving access to the upper trachea} - A61M 25/007: {Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked} - A61M 25/1011: {Multiple balloon catheters} - A61B 6/486: {involving generating temporal series of image data} - A61B 34/20: Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis - A61B 2017/00809: {Lung operations} - A61B 2034/105: {Modelling of the patient, e.g. for ligaments or bones} - A61B 2034/2051: {Electromagnetic tracking systems} - A61B 2034/2072: {Reference field transducer attached to an instrument or patient} - A61B 2090/3925: {ultrasonic} - A61K 9/0073: {Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy; (nasal sprays A61K9/0043; inhalation of vapours of volatile or heated drugs, e.g. essential oils or nicotine, A61K9/007; devices A61M)} - A61M 2025/1052: {for temporarily occluding a vessel for isolating a sector} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) ## Abstract A method and system for instilling a medium into portions of a luminal network is provided. The method includes generating a model of a luminal network based on images of the luminal network, determining a location of a treatment target in the luminal network, navigating a bronchoscope through the bronchial tree to a target, guiding a catheter through the bronchoscope, dispensing medium to the target from a distal end of the catheter, and removing a quantity of medium from the luminal network. ## Claims ### Claim 1 A method of instilling a therapy medium into portions of a luminal network comprising: generating a model of a luminal network based on images of the luminal network; determining a location of a target in the luminal network; guiding a catheter to the target, the catheter including a medium channel and at least one medium outlet in fluid communication with the medium channel for delivering a therapy medium to the target; isolating an area of the luminal network around the target by inflating a first balloon coupled to the catheter and inflating a second balloon coupled to the catheter distal to the first balloon such that the isolated area is disposed between the first and second inflated balloons; passing air through a bypass channel of the catheter, the bypass channel extending distal to the isolated area and extending through the catheter distally beyond a distal end of the medium channel, wherein a distal-most end of the catheter forms a distal opening of the bypass channel through which the air exits the bypass channel for delivery into the luminal network distal to the isolated area of the luminal network; dispensing, via the at least one medium outlet, the therapy medium within the isolated area of the luminal network to the target; removing a volume of the therapy medium from the isolated area of the luminal network; measuring the volume of therapy medium removed from the isolated area of the luminal network; and determining whether the volume of the therapy medium removed from the isolated areas of the luminal network equals or exceeds a threshold volume based on a volume of the therapy medium dispensed to the isolated area of the luminal network. ### Claim 2 (depends on 1) The method of claim 1, further comprising: generating an electromagnetic field about the luminal network; inserting a location sensor into the electromagnetic field; tracking a location of the location sensor coupled to the catheter while the location sensor is navigated within the luminal network; and displaying guidance for navigating the location sensor within the luminal network, wherein the location sensor includes magnetic field sensors configured to sense the magnetic field and to generate position signals in response to the sensed magnetic field. ### Claim 3 (depends on 1) The method of claim 1, wherein the first balloon, when inflated, prevents the therapy medium from advancing past the first balloon such that the therapy medium remains distal to the first balloon. ### Claim 4 (depends on 1) The method of claim 1, wherein the second balloon, when inflated, prevents the therapy medium from advancing such that the medium remains proximal to the second balloon, and the first balloon and the second balloon isolate a volume of the luminal network. ### Claim 5 (depends on 1) The method of claim 1, wherein the therapy medium is one or more of an antibacterial, an antifungal, an antiviral, an immunotherapy solution, a fluid, an aerosol, a powder, an epoxy, and a sealant. ### Claim 6 (depends on 1) The method of claim 1, wherein the therapy medium is dispensed using a manual syringe. ### Claim 7 (depends on 1) The method of claim 1, wherein the therapy medium is dispensed using a pump. ### Claim 8 (depends on 1) The method of claim 1, further comprising: measuring an internal luminal pressure; and halting therapy medium dispensing if the internal luminal pressure exceeds a pressure value. ### Claim 9 A method of instilling a therapy medium into portions of a luminal network comprising: guiding a catheter to a target within the luminal network, the catheter including a medium channel and at least one medium outlet in fluid communication with the medium channel for delivering a therapy medium to the target; isolating an area around the target by inflating a first balloon coupled to the catheter and inflating a second balloon coupled to the catheter distal to the first balloon such that the isolated area is disposed between the first and second inflated balloons; passing air through a bypass channel of the catheter, the bypass channel extending distal to the isolated area and extending through the catheter distally beyond a distal end of the medium channel, wherein a distal-most end of the catheter forms a distal opening of the bypass channel through which the air exits the bypass channel for delivery into the luminal network distal to the isolated area of the luminal network; dispensing, via the at least one medium outlet, the therapy medium within the isolated area of the luminal network to the target; removing a volume of the therapy medium from the isolated area of the luminal network; measuring the volume of therapy medium removed from the isolated area of the luminal network; and determining whether the volume of the therapy medium removed from the isolated area of the luminal network equals or exceeds a threshold volume based on a volume of the therapy medium dispensed within the isolated area of the luminal network. ### Claim 10 (depends on 9) The method of claim 9, wherein the first balloon, when inflated, prevents the therapy medium from advancing past the balloon such that the medium remains distal to the first balloon. ### Claim 11 (depends on 9) The method of claim 9, wherein the second balloon, when inflated, prevents the therapy medium from advancing such that the medium remains proximal to the second balloon, and the first balloon and the second balloon isolate a volume of the luminal network. ### Claim 12 (depends on 9) The method of claim 9, wherein the therapy medium is one or more of an antibacterial, an antifungal, an antiviral, an immunotherapy solution, a fluid, an aerosol, a powder, an epoxy, and a sealant. ### Claim 13 (depends on 9) The method of claim 9, wherein the therapy medium is dispensed using a manual syringe. ### Claim 14 (depends on 9) The method of claim 9, wherein the therapy medium is dispensed using a pump. ### Claim 15 (depends on 9) The method of claim 9, further comprising: measuring an internal luminal pressure; and halting therapy medium dispensing if the internal luminal pressure exceeds a pressure value. ### Claim 16 A method of instilling a therapy medium into portions of a luminal network comprising: guiding a catheter to a target within the luminal network, the catheter including a medium channel and at least one medium outlet in fluid communication with the medium channel for delivering a therapy medium to the target; isolating an area of the luminal network around the target by inflating a first balloon and a second balloon coupled to a distal portion of the catheter until the first balloon contacts walls of the luminal network and the second balloon contacts walls of the luminal network creating a seal between the first balloon and the second balloon; passing air through a bypass channel of the catheter, the bypass channel extending distal to the isolated area and extending through the catheter distally beyond a distal end of the medium channel, wherein a distal-most end of the catheter forms a distal opening of the bypass channel through which the air exits the bypass channel for delivery into the luminal network distal to the isolated area; dispensing, via the at least one medium outlet, the therapy medium within the isolated area of the luminal network to the target; removing a volume of the therapy medium from the isolated area of the luminal network; measuring the volume of therapy medium removed from the isolated area of the luminal network; and determining whether the volume of the therapy medium removed from the luminal network equals or exceeds a threshold volume based on a volume of the dispensed therapy medium. ### Claim 17 (depends on 16) The method of claim 16, wherein the therapy medium is one or more of an antibacterial, an antifungal, an antiviral, an immunotherapy solution, a fluid, an aerosol, a powder, an epoxy, and a sealant.