# US 12,181,544 B2 · RF resonator array device for use in magnetic resonance imaging and methods of use thereof

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- Number: US 12,181,544 B2
- Document ID: US12181544B2
- Status: Granted
- Kind: B2
- Application number: 17/922,912
- Filed: 2021-05-05
- Published: 2023-05-25
- Granted: 2024-12-31
- Earliest claimed: 2020-05-05
- Assignees: Icahn School of Medicine at Mount Sinai
- Applicants: Icahn School of Medicine At Mount Sinai
- Inventors: Akbar Alipour; Priti Balchandani; Alan C. Seifert
- Web page: https://patentgrep.com/patent/US12181544B2

## CPC

- G01R 33/343: of slotted-tube or loop-gap type
- H01P 7/08: Strip line resonators
- A61B 5/055: involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
- G01R 33/34076: {Birdcage coils}
- G01R 33/3642: {Mutual coupling or decoupling of multiple coils, e.g. decoupling of a receive coil from a transmission coil, or intentional coupling of RF coils, e.g. for RF magnetic field amplification}
- G01R 33/5659: {caused by a distortion of the RF magnetic field, e.g. spatial inhomogeneities of the RF magnetic field (G01R33/56509, G01R33/56518, G01R33/56536 take precedence)}
- G01R 33/34007: {Manufacture of RF coils, e.g. using printed circuit board technology; additional hardware for providing mechanical support to the RF coil assembly or to part thereof, e.g. a support for moving the coil assembly relative to the remainder of the MR system}
- G01R 33/3415: comprising arrays of sub-coils {, i.e. phased-array coils with flexible receiver channels}
- G01R: MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES (indicating correct tuning of resonant circuits H03J3/12)
- H01P: WAVEGUIDES; RESONATORS, LINES, OR OTHER DEVICES OF THE WAVEGUIDE TYPE (operating at optical frequencies G02B)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

A radiofrequency (RF) resonator array device for use in magnetic resonance imaging (MRT), The RF resonator array device includes a substrate. An array of coupled split ring resonators are located on the substrate. Each of the coupled split ring resonators includes a first split ring resonator positioned on a first side of the substrate and a second split ring resonator positioned on a second side of the substrate located opposite the first side. The second split ring resonator is inductively coupled to the first split ring resonator. Methods of making and using the RF resonator device are also disclosed.

## Claims

### Claim 1

A radiofrequency resonator array device for use in magnetic resonance imaging (MRI) comprising:
a substrate;
an array of coupled split ring resonators located on the substrate, each of the coupled split ring resonators comprising:
a first split ring resonator positioned on a first side of the substrate;
a second split ring resonator positioned on a second side of the substrate located opposite the first side, the second split ring resonator coupled to the first split ring resonator, and wherein each of the coupled split ring resonators in the array of coupled split ring resonators are configured to generate a local radiofrequency field that increases resonator signal intensity near the coupled split ring resonator during operation of an MRI device.

### Claim 2

A method of making a radiofrequency (RF) resonator array device for use in magnetic resonance imaging (MRI) comprising:
providing a substrate;
locating an array of coupled split ring resonators on the substrate, each of the coupled split ring resonators comprising:
a first split ring resonator positioned on a first side of the substrate; and
a second split ring resonator positioned on a second side of the substrate located opposite the first side, the second split ring resonator coupled to the first split ring resonator, and wherein each of the coupled split ring resonators in the array of coupled split ring resonators are configured to generate a local radiofrequency field that increases resonator signal intensity near the coupled split ring resonator during operation of an MRI device.

### Claim 3

A method of generating a magnetic resonance image (MRI) using an MRI device, the method comprising:
providing a radiofrequency (RF) resonator array device comprising:
a substrate; and
an array of coupled split ring resonators located on the substrate,
each of the coupled split ring resonators comprising:
a first split ring resonator positioned on a first side of the substrate; and
a second split ring resonator positioned on a second side of the substrate located opposite the first side, the second split ring resonator coupled to the first split ring resonator, the second split ring resonator positioned in an orientation rotated 180 degrees with respect to the first split ring resonator, wherein each of the coupled split ring resonators in the array of coupled split ring resonators are configured to generate a local radiofrequency field that increases resonator signal intensity near the coupled split ring resonator during operation of the MRI device;
positioning the RF resonator array device near a portion of a patient's anatomy to be imaged using the MRI device; and
obtaining an MRI image of the portion of the patient's anatomy using the MRI device, wherein the RF resonator array device inductively couples to a magnetic coil of the MRI device during the obtaining to provide additional flux and amplify the receive MR signal during operation of the MRI device.

### Claim 4 (depends on 1)

The device of claim 1, wherein the second split ring resonator is positioned in an orientation rotated 180 degrees with respect to the first split ring resonator.

### Claim 5 (depends on 1)

The device of claim 1, wherein the substrate comprises a dielectric material.

### Claim 6 (depends on 1)

The device of claim 1, wherein the substrate is constructed of a flexible material.

### Claim 7 (depends on 1)

The device of claim 1, wherein the substrate has a thickness between about 50 micrometers and about 500 micrometers.

### Claim 8 (depends on 1)

The device of claim 1, wherein the each of the coupled split ring resonators in the array of coupled split ring resonators are configured to inductively couple to a radiofrequency coil of the MRI device to provide additional flux during a transmit phase of the MRI device during operation of the MRI device.

### Claim 9 (depends on 1)

The device of claim 1, wherein the each of the coupled split ring resonators in the array of coupled split ring resonators are configured to inductively couple to a radiofrequency coil of the MRI device to improve receive MR signal during a receive phase of the MRI device during operation of the MRI device.

### Claim 10 (depends on 1)

The device of claim 1, wherein each of the coupled split ring resonators in the array of coupled split ring resonators is tuned to a resonance frequency that is equal to the Larmor frequency of the MRI device based on a field strength of the MRI device.

### Claim 11 (depends on 1)

The device of claim 1, wherein a location on the substrate of each of the coupled split ring resonators in the array of coupled split ring resonators has an overlap with at least one other one of the coupled split ring resonators in the array of coupled slit ring resonators.

### Claim 12 (depends on 2)

The method of claim 2 further comprising:
positioning each of the coupled split ring resonators in the array of coupled split ring resonators at a location on the substrate to have an overlap with at least one other one of the coupled split ring resonators in the array of coupled split ring resonators.

### Claim 13 (depends on 3)

The method of claim 3, wherein the portion of the patient's anatomy is the patient's brain.

### Claim 14 (depends on 3)

The method of claim 3, wherein the MRI image is obtained at a field strength of at least 7 T.

### Claim 15 (depends on 3)

The method of claim 3, wherein the each of the coupled split ring resonators in the array of coupled split ring resonators inductively couple to a radiofrequency coil of the MRI device to provide additional flux during a transmit phase of the MRI device.

### Claim 16 (depends on 3)

The method of claim 3, wherein the each of the coupled split ring resonators in the array of coupled split ring resonators inductively couple to a radiofrequency coil of the MRI device to improve receive MR signal during a receive phase of the MRI device.

### Claim 17 (depends on 3)

The method of claim 3, wherein each of the coupled split ring resonators in the array of coupled split ring resonators generate a local magnetic field that increases resonator signal intensity near the coupled split ring resonator during operation of the MRI device.

### Claim 18 (depends on 7)

The device of claim 7, wherein the substrate has a thickness of about 200 micrometers.

### Claim 19 (depends on 11)

The device of claim 11, wherein the overlap is based on a critical loop center-to-center distance value to reduce inductive coupling.
