Blood separation and analysis device and methods
Assignee1866402 Ontario Limited
InventorJeffrey Sutton
Life of this patent
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Abstract
There is provided a device and method for separation of blood, including sedimentation of plasma using PVA. The device comprises an inner container enclosed in an outer container, wherein upon alignment of respective openings, allows sample to exit from the inner container into a reaction structure. The reaction structure comprises one or more layers, each with one or more portions each containing concentrations of one or more chemicals.
Claims12
A device for separating a fluid into constituent components comprising:
- an inner container forming a sedimentation compartment for receiving a sample of the fluid, the inner container having an inlet port and a first aperture;
- an outer container for receiving the inner container and having a second aperture;
- a breachable diluent reservoir, wherein upon breach an internal volume of the diluent reservoir is in fluid communication with the sedimentation compartment;
- and
- at least one of the inner container and the outer container being movable between a first configuration where the outer container seals the first aperture and a second configuration wherein the first aperture and the second aperture align to form an outlet for a separated component of the sample fluid;
- wherein the first aperture is sized and shaped such that a volume of sample fluid plus contents of the diluent reservoir will upon settling cover a portion of the first aperture while leaving an air vent at the top.
A device for separating a fluid into constituent components comprising:
- an inner container forming a sedimentation compartment for receiving a sample of the fluid, the inner container having an inlet port and a first aperture;
- an outer container for receiving the inner container and having a second aperture;
- a breachable diluent reservoir, wherein upon breach an internal volume of the diluent reservoir is in fluid communication with the sedimentation compartment;
- at least one of the inner container and the outer container being movable between a first configuration where the outer container seals the first aperture and a second configuration wherein the first aperture and the second aperture align to form an outlet for a separated component of the sample fluid;
- and
- a reaction module in fluid communication with the outlet.
A method of separating plasma from whole blood using a device for separating a fluid into constituent compartments
- the device comprising an inner container forming a sedimentation compartment for receiving a sample of the fluid, the inner container having an inlet port and a first aperture;
- an outer container for receiving the inner container and having a second aperture;
- a breachable diluent reservoir, wherein upon breach an internal volume of the diluent reservoir is in fluid communication with the sedimentation compartment;
- and at least one of the inner container and the outer container being movable between a first configuration where the outer container seals the first aperture and a second configuration wherein the first aperture and the second aperture align to form an outlet for a separated component of the sample fluid;
- and
- the method comprising:
- depositing the whole blood in the sedimentation compartment;
- breaching the diluent reservoir;
- and
- moving at least one of the inner container and the outer container between the first configuration and the second configuration to form the outlet for the separated plasma.
Dependencies are inferred from the claim text.