Tissue healing

A method of treating a tissue site, comprising:

• collecting a tissue sample and placing the tissue sample in a cartridge comprising a well plate, the tissue sample comprising keratinocytes;
• positioning the cartridge within a base unit, the base unit comprising a tissue disaggregator;
• via a processor, activating the base unit to rotate the well plate and operate the tissue disaggregator, wherein the well plate is rotated to align one or more wells in the well plate with the tissue sample and the tissue disaggregator, and wherein operation of the tissue disaggregator separates the tissue sample to form a regenerative epidermal suspension;
• and
• providing the regenerative epidermal suspension to a tissue site such that healing of the tissue site is enhanced.