# US 12,180,191 B1 · 2-[(1H-benzimidazol-2-yl)imino]-5,5-diphenylimidazolidin-4-one as an antimicrobial compound

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- Number: US 12,180,191 B1
- Document ID: US12180191B1
- Status: Granted
- Kind: B1
- Application number: 18/430,400
- Filed: 2024-02-01
- Granted: 2024-12-31
- Earliest claimed: 2023-10-23
- Assignees: King Faisal University
- Applicants: King Faisal University
- Inventors: Mai Mostafa Khalaf Ali; Hany Mohamed Abd El-Lateef Ahmed; Amer A Amer; Antar Ahmed Abdelhamid Ahmed
- Web page: https://patentgrep.com/patent/US12180191B1

## CPC

- C07D 403/12: linked by a chain containing hetero atoms as chain links
- A61P 31/04: Antibacterial agents
- A61P 31/10: Antimycotics
- C07D: HETEROCYCLIC COMPOUNDS (macromolecular compounds C08)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

A 2-[(1H-benzimidazol-2-yl)imino]-5,5-diphenylimidazolidin-4-one compound, its synthesis, and its use as an antimicrobial agent.

## Claims

### Claim 1

A method of treating a microbial infection in a patient comprising administering to a patient in need thereof a therapeutically effective amount of 2-[(1H-benzimidazol-2-yl)imino]-5,5-diphenylimidazolidin-4-one compound, wherein the microbial infection is caused by one or more microbes selected from the group consisting of gram positive bacteria, gram negative bacteria, fungi, and a combination thereof,
wherein the gram positive bacteria is selected from the group consisting of Bacillus cereus, Staphylococcus aureus, and a combination thereof,
wherein the gram negative bacteria is selected from the group consisting of Pseudomonas aeruginosa, Escherichia coli, and a combination thereof, and
wherein the fungi is selected from the group consisting of Aspergillus flavus, Chrysosporium keratinophilum, and a combination thereof.