# US 12,180,170 B1 · 2-(5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)acetic acid as an antimicrobial compound

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- Number: US 12,180,170 B1
- Document ID: US12180170B1
- Status: Granted
- Kind: B1
- Application number: 18/425,970
- Filed: 2024-01-29
- Granted: 2024-12-31
- Earliest claimed: 2023-10-17
- Assignees: King Faisal University
- Applicants: King Faisal University
- Inventors: Hany Mohamed Abd El-Lateef Ahmed; Mai Mostafa Khalaf Ali; Antar Ahmed Abdelhamid Ahmed; Amer A. Amer
- Web page: https://patentgrep.com/patent/US12180170B1

## CPC

- C07D 249/08: 1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- A61P 31/04: Antibacterial agents
- A61P 31/10: Antimycotics
- C07D: HETEROCYCLIC COMPOUNDS (macromolecular compounds C08)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

An 2-(5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)acetic acid compound, its synthesis, and its use as an antimicrobial agent.

## Claims

### Claim 1

A method of treating a microbial infection in a patient comprising administering to a patient in need thereof a therapeutically effective amount of a 2-(5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)acetic acid compound having the formula I:

### Claim 2 (depends on 1)

The method of treating the microbial infection of claim 1, wherein the microbial infection is caused by one or more bacteria or fungi.

### Claim 3 (depends on 2)

The method of treating the microbial infection of claim 2, wherein the microbial infection is caused by one or more gram positive bacteria, one or more gram negative bacteria, one or more fungi, or a combination thereof.

### Claim 4 (depends on 3)

The method of treating the microbial infection of claim 3, wherein the one or more gram positive bacteria are Bacillus cereus, Staphylococcus aureus, or a combination thereof.

### Claim 5 (depends on 3)

The method of treating the microbial infection of claim 3, wherein the one or more gram negative bacteria are Pseudomonas aeruginosa, Escherichia coli, or a combination thereof.

### Claim 6 (depends on 2)

The method of treating the microbial infection of claim 2, wherein the one or more fungi are Aspergillus flavus, Chrysosporium keratinophilum, or a combination thereof.