# US 12,179,013 B2 · Electrode device for wrapping vessel in the body and method therefor

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- Number: US 12,179,013 B2
- Document ID: US12179013B2
- Status: Granted
- Kind: B2
- Application number: 17/638,921
- Filed: 2020-08-27
- Published: 2022-09-22
- Granted: 2024-12-31
- Earliest claimed: 2019-08-29
- Assignees: Deepqure Inc.
- Applicants: Deepqure Inc.
- Inventors: Chang Wook Jeong; Sung Min Park; Jin Hwan Baik; Dong Hyun Yim; Du Jin Bach
- Web page: https://patentgrep.com/patent/US12179013B2

## CPC

- A61N 1/0551: {Spinal or peripheral nerve electrodes}
- A61N 1/0556: {Cuff electrodes}
- A61B 18/00: Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body (eye surgery A61F9/007; ear surgery A61F11/00)
- A61B 18/14: Probes or electrodes therefor
- A61N 1/0558: {Anchoring or fixation means therefor}
- A61B 2017/00867: {shape memory effect}
- A61B 2018/00404: {Blood vessels other than those in or around the heart}
- A61B 2018/00434: {Neural system}
- A61B 2018/1407: {Loop}
- A61B 2018/142: {at least partly surrounding the target, e.g. concave, curved or in the form of a cave}
- A61B 2018/1432: {curved}
- A61N 1/36057: {adapted for stimulating afferent nerves}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

An electrode device for wrapping a vessel in the body according to an embodiment of the present invention comprise an electrode part that surrounds the vessel and denervates or modulates at least some nerves of the vessel; and a guide part that guides movement of the electrode part, wherein the electrode part includes: a first layer that is bent in order for the electrode part to be wound around the vessel; a second layer that is placed on the first layer and is bent in order for the electrode part to be wound in close contact with the vessel; an electrode that is placed on the second layer and denervates or modulates at least some nerves of the vessel with energy from an energy source generator.

## Claims

### Claim 1

An electrode device for wrapping a vessel in a body, comprising:
an electrode part configured to surround the vessel and configured to denervate or modulate at least some nerves of the vessel; and
a guide part that guides movement of the electrode part,
wherein the electrode part includes:
a first layer configured to be bent such that the electrode part is wound around the vessel;
a second layer that is placed on the first layer and configured to be bent such that the electrode part is wound in close contact with the vessel;
an electrode placed on the second layer and configured to perform the denervation or modulation of the at least some nerves of the vessel using energy received from an energy source generator,
wherein at least a portion of the first layer is made of a shape memory alloy, and
the shape memory alloy is bent with a first curvature at a first transformation temperature or higher and bent with a second curvature at a second transformation temperature or higher.

### Claim 2 (depends on 1)

The electrode device of claim 1,
wherein the first layer is configured to be heated to the first transformation temperature by body temperature.

### Claim 3 (depends on 1)

The electrode device of claim 1,
wherein the first layer is configured to be heated to the second transformation temperature by the energy received from the energy source generator.

### Claim 4 (depends on 1)

The electrode device of claim 1,
wherein the second curvature is smaller than the first curvature.

### Claim 5 (depends on 1)

The electrode device of claim 1,
wherein the first transformation temperature ranges from 35° C. to 40° C. and the second transformation temperature ranges from 50° C. to 60° C.

### Claim 6 (depends on 1)

The electrode device of claim 1,
wherein the shape memory alloy is a bidirectional shape memory alloy.

### Claim 7 (depends on 6)

The electrode device of claim 6,
wherein the bidirectional shape memory alloy is unbent straight at a third transformation temperature or lower.

### Claim 8 (depends on 7)

The electrode device of claim 7,
wherein the third transformation temperature ranges from 20° C. to 25° C.

### Claim 9 (depends on 1)

The electrode device of claim 1,
wherein the second layer forms an inner space through which a gas or fluid flows, and one surface of the second layer adjacent to the first layer is fixed and attached to the first layer and another surface of the second layer, opposite to the one surface, is not fixed to the first layer.

### Claim 10 (depends on 9)

The electrode device of claim 9,
wherein the electrode device is configured such that after the first layer surrounds the vessel, a volume of the second layer is changed to adjust a diameter of the second layer so as to correspond to a diameter of the vessel.

### Claim 11

An electrode device for wrapping a vessel in a body, comprising:
an electrode part configured to surround the vessel and configured to denervate or modulate at least some nerves of the vessel; and
a guide part that guides movement of the electrode part,
wherein the electrode part includes:
a first layer configured to be bent such that the electrode part is wound around the vessel;
a second layer that is placed on the first layer and configured to be bent such that the electrode part is wound in close contact with the vessel;
an electrode placed on the second layer and configured to perform the denervation or modulation of the at least some nerves of the vessel using energy received from an energy source generator,
wherein the first layer and the second layer are fixed and connected only at one respective end of each, and adjacent surfaces thereof are not attached to each other.

### Claim 12 (depends on 11)

The electrode device of claim 11,
wherein the electrode device is configured such that after the first layer surrounds the vessel, the second layer is pulled toward the guide part to adjust a diameter of the second layer so as to correspond to a diameter of the vessel.

### Claim 13

A method of wrapping a vessel in a body by using an electrode device including: an electrode part that includes a first layer, a second layer and an electrode arranged sequentially, the electrode part configured to surround the vessel and configured to denervate or modulate at least some nerves of the vessel; and a guide part configured to guide movement of the electrode part, the method comprising:
bending the first layer such that the electrode part is wound around the vessel;
bending the second layer such that the electrode part to be is wound in close contact with the vessel; and
denervating or modulating the at least some nerves of the vessel with the electrode, using energy received from an energy source generator,
wherein at least a portion of the first layer is made of a shape memory alloy, and
the shape memory alloy is bent with a first curvature at a first transformation temperature or higher and bent with a second curvature at a second transformation temperature or higher.

### Claim 14 (depends on 5)

The method of claim 5,
wherein the bending of the first layer such that the electrode part is wound around the vessel includes:
heating the first layer to the first transformation temperature by body temperature; and
heating the first layer to the second transformation temperature by the energy received from the energy source generator.

### Claim 15 (depends on 13)

The method of claim 13,
wherein the bending of the second layer is such that the electrode part is wound in close contact with the vessel includes:
pulling the second layer toward the guide part to adjust a diameter of the second layer so as to correspond to a diameter of the vessel.

### Claim 16 (depends on 13)

The method of claim 13,
wherein the bending of the second layer such that the electrode part is wound in close contact with the vessel includes:
a process in which a volume of the second layer is changed to adjust a diameter of the second layer so as to correspond to a diameter of the vessel.
