# US 12,178,979 B2 · Dermal patch for delivering a pharmaceutical

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- Number: US 12,178,979 B2
- Document ID: US12178979B2
- Status: Granted
- Kind: B2
- Application number: 18/090,107
- Filed: 2022-12-28
- Published: 2023-07-27
- Granted: 2024-12-31
- Earliest claimed: 2021-10-13
- Assignees: Satio, Inc.
- Applicants: Satio, Inc.
- Inventors: Namal Nawana; Ziad Tarik Al-Shamsie
- Web page: https://patentgrep.com/patent/US12178979B2

## CPC

- A61M 5/14248: {of the skin patch type}
- A61M 37/0015: {by using microneedles}
- A61M 5/14212: {Pumping with an aspiration and an expulsion action}
- A61M 2005/1402: {Priming}
- A61M 2005/14252: {with needle insertion means}
- A61M 2037/0023: {Drug applicators using microneedles}
- A61M 2037/0061: {Methods for using microneedles}
- A61M 2202/30: Vaccines
- A61M 2205/6063: Optical identification systems
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

A dermal patch system for administering a pharmaceutical includes a vial that stores a pharmaceutical and a cartridge coupled to the vial. The cartridge includes a pull mechanism, a pump, a plurality of microneedles in communication with the vial. The microneedles are configured to move between an undeployed position to a deployed position. When pulled, the pull mechanism is configured to cause the microneedles to move from the undeployed position to the deployed position and cause the pump to pump the pharmaceutical from the vial and to the microneedles.

## Claims

### Claim 1

A dermal patch system for administering a pharmaceutical comprising:
a vial that stores a pharmaceutical, and
a cartridge coupled to the vial, wherein the dermal patch includes:
a pull mechanism,
a pump, and
a plurality of microneedles in communication with the vial, wherein the microneedles are configured to move between an undeployed position to a deployed position,
wherein, when pulled, the pull mechanism is configured to cause the pump to pump the pharmaceutical from the vial and to the microneedles, and cause the microneedles to move to the deployed position, and
wherein the pump comprises a pump portion having a cog, wherein the cog includes a plurality of protrusions that are configured to compress a tube as the cog rotates thereby causing the pharmaceutical to be expelled from the vial.

### Claim 2 (depends on 1)

The dermal patch system of claim 1, wherein the pump is configured to prime the microneedles with an amount of pharmaceutical before the microneedles are moved to the deployed position.

### Claim 3 (depends on 1)

The dermal patch system of claim 1, wherein the cartridge further includes:
a tube configured to carry the pharmaceutical from the vial to the plurality of microneedles.

### Claim 4 (depends on 3)

The dermal patch system of claim 3, wherein pulling the pull mechanism causes the pump to rotate which causes the pump to force the pharmaceutical through the tube via positive displacement.

### Claim 5 (depends on 4)

The dermal patch system of claim 4, wherein the tube is a first tube, and the cartridge includes a second tube connected to the vial, and wherein rotation of the pump further causes the pump to force air into the vial through the second tube via positive displacement.

### Claim 6 (depends on 4)

The dermal patch system of claim 4, wherein the cartridge further includes: a latch that allows the pump to rotate in a first direction and prevents the pump from rotating in an opposite second direction.

### Claim 7 (depends on 1)

The dermal patch system of claim 1, wherein the pull mechanism is configured to move when then the cartridge has a first orientation and is prevented from moving when the cartridge has a different second orientation.

### Claim 8 (depends on 1)

The dermal patch system of claim 1, wherein the cartridge further includes:
a trigger that is configured to move from a first position to a second position when the pull mechanism is pulled,
wherein in the first position the trigger retains the microneedles in the undeployed position and configured to release the microneedles in the second position.

### Claim 9 (depends on 8)

The dermal patch system of claim 8, wherein the pump is configured to move the trigger from the first position to the second position when the pull mechanism is pulled.

### Claim 10 (depends on 8)

The dermal patch system of claim 8, wherein the cartridge further includes an injection spring that is in a compressed state when the trigger is in the first position and in an extended state when the trigger is in the second position, and wherein the injection spring is configured to move the microneedles to the deployed position when in the extend position.

### Claim 11 (depends on 1)

The dermal patch system of claim 1, wherein the cartridge further includes: a retraction button configured to move the microneedles from the deployed position to the undeployed position.

### Claim 12 (depends on 11)

The dermal patch system of claim 11, wherein the retraction button is prevented from moving the microneedles when the microneedles are in the undeployed position.

### Claim 13 (depends on 1)

The dermal patch system of claim 1, wherein the cartridge further includes: a latch that prevents a user from removing the vial from the cartridge.

### Claim 14 (depends on 1)

The dermal patch system of claim 1, wherein the pharmaceutical is a vaccine.

### Claim 15 (depends on 13)

The dermal patch system of claim 13, wherein the vial includes a fractional dose of the vaccine.

### Claim 16 (depends on 1)

The dermal patch system of claim 1, wherein the cartridge includes a quick response code that is
associated with an electronic medical record.
