# US 12,178,952 B2 · Injection cannula, ECMO system

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- Number: US 12,178,952 B2
- Document ID: US12178952B2
- Status: Granted
- Kind: B2
- Application number: 17/310,112
- Filed: 2020-01-21
- Published: 2022-03-03
- Granted: 2024-12-31
- Earliest claimed: 2019-01-28
- Assignees: Assistance Publique-Hopitaux de Paris
- Applicants: Assistance Publique Hopitaux De Paris
- Inventors: Pierre Mordant
- Web page: https://patentgrep.com/patent/US12178952B2

## CPC

- A61M 1/3659: {Cannulae pertaining to extracorporeal circulation}
- A61M 25/04: in the body, e.g. expansible {(A61M25/10, A61M16/0488 take precedence)}
- A61L 29/08: Materials for coatings
- A61M 1/1698: {Blood oxygenators with or without heat-exchangers (intracorporal A61M1/1678; manufacturing of membranes therefor B01D67/00; semi-permeable membranes for separation processes characterised by their properties B01D69/00; semi-permeable membranes characterised by their material B01D71/00)}
- A61M 1/3623: {Means for actively controlling temperature of blood}
- A61M 25/0026: {Multi-lumen catheters with stationary elements (catheter assemblies comprising a catheter in combination with a guide tube, sheath or sleeve A61M2025/0681; catheters comprising telescoping coaxial elements A61M2025/0175)}
- A61M 25/007: {Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked}
- A61M 25/0074: {Dynamic characteristics of the catheter tip, e.g. openable, closable, expandable or deformable}
- A61L 2300/42: Anti-thrombotic agents, anticoagulants, anti-platelet agents
- A61M 25/0029: {characterized by features relating to least one lumen located at the middle part of the catheter, e.g. slots, flaps, valves, cuffs, apertures, notches, grooves or rapid exchange ports (catheter shaft surface irregularities A61M2025/006)}
- A61M 25/0108: {using radio-opaque or ultrasound markers}
- A61M 2025/0031: {characterized by lumina for withdrawing or delivering, i.e. used for extracorporeal circuit treatment}
- A61M 2025/0056: {provided with an antibacterial agent, e.g. by coating, residing in the polymer matrix or releasing an agent out of a reservoir}
- A61M 2205/0266: Shape memory materials
- A61M 2205/36: related to heating or cooling
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)

## Abstract

The invention relates to a cannula (1) for injecting a fluid (F1) into a body cavity (5), comprising: a main lumen (LP) for the fluid to flow in a first direction; an accessory reperfusion lumen (LA) comprising an outlet (20′) for discharging the fluid in a second direction; and a device for positioning the cannula in the cavity, the device comprising a stop (41) which can move along an auxiliary lumen (LX) and be deployed in the cavity in order to lock the cannula in position in the cavity, the outlet (30′) of the auxiliary lumen being arranged at a distance (d) from the outlet (20′) of the accessory reperfusion lumen such that when the cannula is locked in position in the cavity, the outlet (20′) of the accessory reperfusion lumen (LA) is oriented in the cavity such that the collected fluid is discharged in the second direction.

## Claims

### Claim 1

A cannula for injecting a fluid into a cavity of the human or animal body, comprising:
a main lumen defining a first space of the cannula for the fluid to flow in a first direction; and
an accessory reperfusion lumen defining a second space of the cannula and comprising:
an inlet for collecting a portion of the fluid flowing in the first direction;
an angled portion for changing the direction of flow of the fluid collected by the accessory reperfusion lumen; and
an outlet for discharging the collected fluid in a second direction into the cavity;
a stop configured to move along an auxiliary lumen so as to position the cannula in the cavity, the auxiliary lumen (LX) defining a third space of the cannula and comprising an outlet opening into the cavity; and
a connector connected to the stop and extending along the auxiliary lumen,
the stop being further configured to be deployed in the cavity, via the outlet of the auxiliary lumen, in order to ensure that the cannula is locked in position in the cavity,
the outlet of the auxiliary lumen being arranged at a predetermined distance from the outlet of the accessory reperfusion lumen such that when the stop locks the cannula in position in the cavity, the outlet of the accessory reperfusion lumen is oriented in the cavity such that the collected fluid is discharged in the second direction,
wherein the connector is configured to move the stop along the auxiliary lumen.

### Claim 2 (depends on 1)

The cannula according to claim 1, wherein the predetermined distance between the outlet of the auxiliary lumen and the outlet of the accessory reperfusion lumen is between 0.1 and 500 mm.

### Claim 3 (depends on 1)

The cannula according to claim 1, wherein the stop is configured to be moved via a push-button capable of moving in a longitudinal groove provided in the cannula, the movement of the push-button in the longitudinal groove causing the stop to be moved along the auxiliary lumen.

### Claim 4 (depends on 1)

The cannula according to claim 1, wherein the deployed stop has a shape and dimensions designed to prevent the cannula from being withdrawn when inserted inside the cavity.

### Claim 5 (depends on 1)

The cannula according to claim 1, wherein the stop is made from a shape memory material.

### Claim 6 (depends on 1)

The cannula according to claim 1, wherein the stop is made from a nickel-titanium alloy wire.

### Claim 7 (depends on 1)

The cannula according to claim 1, wherein the deployed stop is diamond-shaped.

### Claim 8 (depends on 1)

The cannula according to claim 1, wherein the stop has an anti-thrombogenic and/or anti-proliferative coating.

### Claim 9 (depends on 1)

The cannula according to claim 1, wherein the stop and/or the outlet of the auxiliary lumen has/have a radio-opaque or echo-opaque marking designed to allow said stop and/or the outlet of said auxiliary lumen to be identified by radiography or echography.

### Claim 10 (depends on 1)

The cannula according to claim 1 further comprising a bleed valve connected to the accessory reperfusion lumen.

### Claim 11 (depends on 1)

A system for injecting a fluid into a cavity of the human or animal body, comprising:
an intake cannula for receiving a predetermined fluid;
a pump for pumping the predetermined fluid coming from the intake cannula;
an oxygenator for oxygenating the predetermined fluid coming from an outlet of the pump; and
the cannula according to claim 1 for injecting the oxygenated fluid into the cavity.