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US 12,178,887 B2Granted
NIR-conjugated tumor-specific antibodies and uses thereof
AssigneesCity of Hope, The Regents of the University of California
InventorsPaul Yazaki, Jack Shively, Michael Bouvet, Jonathan Delong, Yuman Fong
Life of this patent
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Abstract
Disclosed is a tumor-specific antibody and fluorophore conjugate for detecting, localizing and imaging of various tumors. Also disclosed are methods for detecting, localizing and imaging a solid tumor before or during a tumor resection surgery using the antibody-fluorophore conjugate.
Claims6
An antibody-fluorophore conjugate comprising a tumor-specific antibody conjugated to a PEG modified NIR fluorophore, wherein the antibody is an anti-TAG-72 antibody, wherein the NIR fluorophore is
Dependencies are inferred from the claim text.